Evidence map›Paper›PMID 40557784›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026

Feasibility and effectiveness of the novel HemoClear microfiltration cell-salvage system in cesarean sections in South Africa.

Nndwammbi C Ramatsea, Marnus Booyens, Joseph B Sempa, Angélique B van 't Wout, Edwin Turton, Arno P Nierich

Abstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Feasibility and effectiveness of the novel HemoClear microfiltration cell-salvage system in cesarean sections in South Africa.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nndwammbi C RamatseaDepartment of Anaesthesiology, The University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0009-0006-2238-3251
Marnus BooyensDepartment of Anaesthesiology, The University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0000-0002-2688-0208
Joseph B SempaDepartment of Biostatistics, The University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0000-0003-1062-0417
Angélique B van 't WoutAlphaBiomics Limited, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0003-3705-2392
Edwin TurtonDepartment of Anaesthesiology, The University of the Free State, Bloemfontein, South Africa.ORCID https://orcid.org/0000-0001-6916-7691
Arno P NierichHemoClear BV, Zwolle, The Netherlands.ORCID https://orcid.org/0000-0003-1221-7277

Funding

Universiteit van die Vrystaat
6 · The paper itself

Abstract

objectiveTo test the feasibility and effectiveness of implementing the HemoClear microfiltration cell-salvage system for cesarean sections in South Africa.

methodsWe conducted a prospective experimental single-arm feasibility study collecting and processing blood from 20 adult women undergoing cesarean section in Pelonomi Tertiary Hospital, Bloemfontein. Samples obtained from the blood salvaged during the cesarean section before (baseline) and after (concentrate and filtrate) the cell-salvage procedure were tested for cellular, protein, electrolyte, and metabolic parameters, as well as blood coagulation and bacterial or amniotic fluid contamination.

resultsMedian erythrocyte recovery using the HemoClear device was 75.5% (interquartile range [IQR], 63.8%-94.3%). An average volume of 826 ± 146 mL was processed in 15.3 ± 6.3 min, resulting in 266 ± 116 mL of cell concentrate. The filtration procedure washed away >75% of the α-fetoprotein content in the concentrate, resulting in a median recovery of 24.0% (IQR, 21.4%-35.9%). Bacterial contamination was mostly consistent between baseline and concentrate for each patient and resulted mainly from normal skin flora. In six patients, nonskin species were detected.

conclusionThis study shows the HemoClear system's adaptability to resource-constrained environments, which opens the door for broader adoption of its use in similar resource-constrained settings. The HemoClear cell-salvage device is safe and efficient for intraoperative use in obstetric hemorrhage cases and can play an essential role in patient blood management.

Indexed as

Blood Transfusion, AutologousCesarean SectionOperative Blood SalvageAdultFeasibility StudiesFemaleFiltrationHumansPregnancyProspective StudiesSouth Africacesarean sectionHemoClearhemorrhageintraoperative cell salvagelow‐middle–income countriestransfusion

Identifiers

PMID40557784
PMCPMC12724054

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.