Evidence map›Paper›PMID 40557755›Full record

ArticleThe International journal of artificial organs2025

Left ventricular assist device exchanges: A safe and effective strategy in the era of limited organ availability.

Nandini Nair, Kenny Nguyen, Dongping Du, Aditya Mahesh, Behzad Soleimani, Balakrishnan Mahesh

Abstract read
In one paragraph

Article in The International journal of artificial organs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nandini NairDivision of Cardiology, Penn State College of Medicine, Hershey, PA, USA.ORCID 0000-0002-1243-4389
Kenny NguyenDivision of Cardiothoracic Surgery, Penn State College of Medicine, Hershey, PA, USA.
Dongping DuIMSE, Texas Tech University, Lubbock, TX, USA.
Aditya MaheshDivision of Cardiothoracic Surgery, Penn State College of Medicine, Hershey, PA, USA.
Behzad SoleimaniDivision of Cardiothoracic Surgery, Penn State College of Medicine, Hershey, PA, USA.
Balakrishnan MaheshDivision of Cardiothoracic Surgery, Penn State College of Medicine, Hershey, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOngoing donor-organ shortage has limited transplantation making LVADs an effective alternative therapy for patients with end-stage heart failure. When LVAD-associated complications arise device exchange is a feasible and safe alternative. This study addresses the factors that impact survival post-LVAD exchange.

methodsOur decoded database was constructed retrospectively. Surgical details, device features, and re-intervention information were studied. The primary outcome was mortality. Kaplan-Meier estimators were used for post-pump exchange survival analysis. Pairwise log-rank tests compare the survivals between different groups within each variable.

resultsAnalysis of factors impacting survival post-pump exchange study showed a poor survival probability of only primary midline-sternotomy/redo (

conclusionsThe overall survival probability is 50% at 4 years post-pump exchange. This study highlights the differences in post-exchange outcomes depending on the device types and surgical approaches used. LVAD exchange for device-related complications can be performed in high-risk patients as a viable alternative to heart transplantation in the setting of the current heart allocation prioritization systems.

Indexed as

Device RemovalHeart-Assist DevicesHeart FailureTissue DonorsAdultAgedFemaleHumansKaplan-Meier EstimateMaleMiddle AgedReoperationRetrospective StudiesRisk FactorsTreatment Outcomelong-term survival post pump exchangeLVADoverall survival post pump exchangepump exchangesurgical approaches to pump exchange

Identifiers

PMID40557755
PMCPMC12332217

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.