Evidence map›Paper›PMID 40557725›Full record

ArticleVeterinary medicine and science2025

Different Aspects of Letrozole Effect on Metabolism, Bone Health, Oxidative Stress and Prostate in the Intact Adult Dog.

Zahra Dadvand, Dorsa Zahedtalab, Maryam Barzegar Bafruei, Nooshin Derakhshandeh, Asghar Mogheiseh, Saeed Nazifi, Mohammad Reza Divar, Mahboobeh Ashrafi

Abstract read
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zahra DadvandDepartment of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Dorsa ZahedtalabDepartment of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Maryam Barzegar BafrueiDepartment of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Nooshin DerakhshandehDepartment of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.ORCID 0000-0003-1752-6028
Asghar MogheisehDepartment of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.ORCID 0000-0002-3136-2288
Saeed NazifiDepartment of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.ORCID 0000-0002-5501-1028
Mohammad Reza DivarDepartment of Clinical Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.
Mahboobeh AshrafiDepartment of Basic Sciences, School of Veterinary Medicine, Shiraz University, Shiraz, Iran.

Funding

Research Council of Shiraz UniversitySchool of Veterinary Medicine 96INT1M154630
6 · The paper itself

Abstract

Letrozole enhances male fertility by balancing oxidative stress and altering the hormonal regulation of spermatogenesis. The study aimed to determine the effect of short-term letrozole administration on the concentration of canine prostatic-specific esterase, parathormone, insulin-like growth factor, vitamin D, alkaline phosphatase, lactate dehydrogenase, creatinine kinase, calcium, magnesium, cholesterol, and triglyceride in the serum of dogs. Moreover, total antioxidant capacity and lipid peroxidation were detected in intact adult dogs

Indexed as

Aromatase InhibitorsBone and BonesLetrozoleOxidative StressProstateAnimalsDogsMaleSemenAromatase InhibitorsLetrozolearomatase inhibitorsdogoxidative stressprostatevitamin D

Identifiers

PMID40557725
PMCPMC12188276

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.