ArticleAnnals of surgery open : perspectives of surgical history, education, and clinical approaches2025
Prospective Observational Study on Perioperative Dysgeusia and Trace Metal Elements in Patients Undergoing Pancreatoduodenectomy.
Article in Annals of surgery open : perspectives of surgical history, education, and clinical approaches, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aimed to evaluate the nature of perioperative dysgeusia and its associated factors in patients undergoing pancreatoduodenectomy (PD). Background: Perioperative dysgeusia is an unfavorable symptom associated with malnutrition. Methods: The Taste Alteration Survey and Trace Elements in patients undergoing PD (TASTE-PD) study was a single-center prospective observational study performed between April 2021 and September 2022. Dysgeusia was evaluated using a questionnaire administered to 100 patients undergoing PD during hospitalization. A blood examination was also performed for the detection of trace metal elements. Statistical analyses were performed between patients with and without preoperative dysgeusia and between those with and without postoperative dysgeusia. Results: Thirty-three (33%) patients experienced dysgeusia during hospitalization (11 with preoperative dysgeusia and 22 with postoperative dysgeusia). Preoperative albumin (3.7 vs 3.9 g/dL, Conclusions: One-third of the patients experienced dysgeusia. Hypoalbuminemia and anemia were associated with preoperative dysgeusia, and advanced age and insufficient iron recovery were associated with postoperative dysgeusia. Further studies will be conducted to evaluate the impact of iron supplementation for improving dysgeusia and postoperative nutritional status.
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