Evidence map›Paper›PMID 40557328›Full record

ArticleDystonia (Lausanne, Switzerland)2025

Subtle changes in Purkinje cell firing in Purkinje cell-specific

Hong Xing, Pallavi Girdhar, Yuning Liu, Fumiaki Yokoi, David E Vaillancourt, Yuqing Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dystonia (Lausanne, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Sex-specific alterations of Purkinje cell firing inDystonia (Lausanne, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hong XingNorman Fixel Institute of Neurological Diseases, McKnight Brain Institute, and Department of Neurology, College of Medicine, University of Florida, Gainesville, FL 32610-0236, USA.
Pallavi GirdharNorman Fixel Institute of Neurological Diseases, McKnight Brain Institute, and Department of Neurology, College of Medicine, University of Florida, Gainesville, FL 32610-0236, USA.
Yuning LiuNorman Fixel Institute of Neurological Diseases, McKnight Brain Institute, and Department of Neurology, College of Medicine, University of Florida, Gainesville, FL 32610-0236, USA.
Fumiaki YokoiNorman Fixel Institute of Neurological Diseases, McKnight Brain Institute, and Department of Neurology, College of Medicine, University of Florida, Gainesville, FL 32610-0236, USA.
David E VaillancourtDepartment of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
Yuqing LiNorman Fixel Institute of Neurological Diseases, McKnight Brain Institute, and Department of Neurology, College of Medicine, University of Florida, Gainesville, FL 32610-0236, USA.

Funding

Non-Invasive Markers of Neurodegeneration in Movement DisordersR01NS075012 · NINDS · UNIVERSITY OF FLORIDA · PI LI, YUQING, VAILLANCOURT, DAVID E · 2012 to 2022
$4.1M
Supplement: Pathophysiology of DYT1 dystonia: Targeted Mouse ModelsR01NS129873 · NINDS · UNIVERSITY OF FLORIDA · PI YUQING LI · 2022 to 2026
$1.9M
Striatal Contribution to the Motor Symptoms and Aphasia in GRN-FTDR03AG087418 · NIA · UNIVERSITY OF FLORIDA · PI LI, YUQING · 2024 to 2024
$305k
NIA NIH HHS R03 AG087418NINDS NIH HHS R01 NS075012NINDS NIH HHS R01 NS129873
6 · The paper itself

Abstract

DYT1 dystonia is an inherited early-onset generalized dystonia characterized by sustained muscle contractions causing abnormal, repetitive movements or postures. Most DYT1 patients have a heterozygous trinucleotide GAG deletion (

Indexed as

cerebellumdystoniaDYT1electrophysiologyPurkinje cellstorsinA

Identifiers

PMID40557328
PMCPMC12186274

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.