ArticlePlastic and reconstructive surgery. Global open2025
An Assessment of the Longitudinal Impact of Gender-affirming Care in an Adolescent and Young Adult Transmasculine and Nonbinary Patient Population.
Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Mental Health, Gender Dysphoria, and Quality of Life in Trans Individuals Following Top Surgery: Protocol for a Prospective Cohort Study.JMIR research protocols · 2026Article
- Surgical and hormonal gender-affirming care: cross-domain determinants and artificial intelligence-enabled expansion.International journal for equity in health · 2026Review
- Rapid review of gender-affirming healthcare for children and adolescents: Evidence synthesis (2021-2025) and recommendations for South Africa.Southern African journal of HIV medicine · 2026Review
- Rapid Review of Gender-Affirming Healthcare for Children and Adolescents: Evidence Synthesis (2021-2025) and Recommendations for South Africa.Research square · 2025Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Gender-affirming care (GAC) during adolescence is associated with decreased adverse gender dysphoria-related outcomes and steadily improved psychological functioning into young adulthood. This single-institution, longitudinal study examined the impact of GAC on various treatment outcomes for transgender and nonbinary adolescents and young adults. Participants included 110 transmasculine and nonbinary adolescents and young adults who were referred for gender-affirming top surgery through the Center for Gender-Affirming Care and Plastic Surgery multidisciplinary clinic at Rady Children's Hospital, San Diego. Methods: Outcomes were assessed via the Patient Health Questionnaire-2, chest and gender dysphoria scales, and surgical satisfaction scales, which were administered at various time points throughout treatment. Multilevel modeling was used to evaluate the impact of GAC on depressive symptoms, chest and gender dysphoria, and surgical satisfaction over time. Results: Significant reductions were observed in patient-reported depressive symptoms, gender dysphoria, and chest dysphoria before and after surgery. On average, survey results indicated that patients reported positive perceptions of their surgical experience, were satisfied with their surgical outcome, and had a positive recovery experience. Conclusions: Results suggest that GAC appears to have a measurable and beneficial impact on patients' mental health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.