ArticleProceedings (Baylor University. Medical Center)2025
Pregnancy outcomes in Fontan circulation: a systematic review and meta-analysis.
Article in Proceedings (Baylor University. Medical Center), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Fontan and pregnancy: walking a tightrope.Proceedings (Baylor University. Medical Center) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Fontan surgery outcomes have significantly improved, leading to an increased number of patients surviving into adulthood. However, data on pregnancy outcomes in this population remain limited. Methods: A systematic search was conducted across four databases, including PubMed, Embase, Web of Science, and Cochrane CENTRAL, from inception to September 25, 2024, without language restrictions. Studies involving pregnancies in women with Fontan circulation that reported maternal or neonatal outcomes were included. Case series and case reports were excluded. Results: A total of 18 studies met the eligibility criteria, including 400 pregnant women with Fontan circulation and 1260 pregnancies. An increase in maternal arrhythmias was observed, with a pooled incidence of 6.59% (95% CI 3.22%-10.83%), all of which were supraventricular tachycardia. The pooled incidence of maternal heart failure was 3.71% (95% CI 0.94%-7.67%), with no report of maternal mortality. Preterm delivery was common, with a pooled incidence of 57.31% (95% CI 40.19%-73.66%). Furthermore, the pooled incidence of neonatal mortality was 4.38% (95% CI 2.08%-7.23%), mainly due to complications from preterm births. Conclusion: Pregnancy in women with Fontan circulation is associated with maternal and neonatal adverse outcomes. Preconception counseling and multidisciplinary care are essential for supporting pregnancy planning, ensuring careful monitoring, and improving pregnancy outcomes.
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