Evidence map›Paper›PMID 40557205›Full record

ArticleProceedings (Baylor University. Medical Center)2025

Early onset gastric cancer: clinical and molecular insights into a rising epidemic among younger adults.

Maryana Stryelkina, My Nguyen, Priyanka Reddy, Anh Trinh Doan, Michelle Min, Lisa Go, Lucas Wong

Abstract read
In one paragraph

Article in Proceedings (Baylor University. Medical Center), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Insights on the rising epidemic of early onset gastric cancer.Proceedings (Baylor University. Medical Center) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maryana StryelkinaDivision of Internal Medicine, Department of Medicine, Baylor Scott & White Medical Center, Temple, Texas, USA.ORCID https://orcid.org/0009-0005-1864-9793
My NguyenDivision of Internal Medicine, Department of Medicine, Baylor Scott & White Medical Center, Temple, Texas, USA.
Priyanka ReddyDivision of Internal Medicine, Department of Medicine, Baylor Scott & White Medical Center, Temple, Texas, USA.
Anh Trinh DoanDivision of Internal Medicine, Department of Medicine, Baylor Scott & White Medical Center, Temple, Texas, USA.
Michelle MinDivision of Internal Medicine, Department of Medicine, Baylor Scott & White Medical Center, Temple, Texas, USA.
Lisa GoDivision of Internal Medicine, Department of Medicine, Baylor College of Medicine, Temple, Texas, USA.
Lucas WongDivision of Hematology Oncology, Department of Medicine, Baylor Scott & White Medical Center, Temple, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early onset gastric cancer (EOGC), defined as gastric cancer occurring in individuals aged 49 years or younger, presents distinct clinical and molecular characteristics compared to late-onset gastric cancer (LOGC). Despite the increasing incidence of EOGC, limited data exist regarding its demographic, risk factor, and molecular profiles. This study aimed to compare the clinicopathologic and molecular features of EOGC and LOGC and characterize the demographic, clinical, and molecular characteristics of EOGC in a diverse cohort to elucidate potential risk factors and disease behavior. Methods: A retrospective cohort study was conducted on 437 gastric carcinoma patients screened at Baylor Scott & White Health (2002-2022). Demographic, clinical, and molecular data, including Results: Of the 437 gastric carcinoma cases screened, 32 patients had EOGC, while 51 had LOGC with available clinical and molecular data. EOGC was associated with a higher proportion of females ( Conclusion: This study underscores the aggressive nature of EOGC, highlighting its advanced-stage presentation, poor survival, and distinct molecular pathways. The high prevalence of

Indexed as

Advanced stage gastric cancerearly onset gastric cancerHelicobacter pyloriHER2microsatellite instabilitysignet ring cell carcinoma

Identifiers

PMID40557205
PMCPMC12184178

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.