Evidence map›Paper›PMID 40557111›Full record

ArticleOpen veterinary journal2025

Biochemical markers of cell death: Forensic implications for differentiating primary and secondary hypothermia.

Emina Dervišević, Aida Bešić, Hajrudin Spahović, Ekrema Mujarić, Nedim Šuta, Muamer Dervišević, Edina Lazović, Aida Selmanagić

Abstract read
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Emina DerviševićDepartment of Forensic Medicine, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Aida BešićDepartment of Clinical Sciences, Faculty of Veterinary Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Hajrudin SpahovićUrology Clinic, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Ekrema MujarićCantonal Hospital Zenica, Zenica, Bosnia and Herzegovina.
Nedim ŠutaDepartment of Biology, Faculty of Science, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Muamer DerviševićUniversity Clinical Center-Clinic for Lung Diseases and Tuberculosis "Podhrastovi", Sarajevo, Bosnia and Herzegovina.
Edina LazovićDepartment of Pathology, Faculty of Medicine, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.
Aida SelmanagićDepartment of Tooth Morphology with Dental Anthropology and Forensics, School of Dentistry, University of Sarajevo, Sarajevo, Bosnia and Herzegovina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Primary hypothermia occurs when the body is exposed to extremely low temperatures in an environment with no underlying health conditions. Secondary hypothermia, on the other hand, results from disruptions in thermoregulation due to diseases, trauma, surgery, drugs, alcohol, or infections. Postmortem biochemistry has become a crucial factor in forensic examinations, offering valuable apprehension into tissue of and organ dysfunction associated with the process of dying. Aim: This research aims to explore various biochemical markers and their significance in distinguishing primary from secondary hypothermia. Methods: This study involved 21 Wistar rats, which were separated into three experimental groups: CG ( Results: Distinct biochemical differences were noted between primary and secondary hypothermia. Glucose and creatinine levels exhibited significant variations ( Conclusion: The calculated osmolality exhibited significant variation among the different groups, indicating a notable impact of the substances on the biochemical profile related to hypothermia. This study focused on the effectiveness of biochemical markers in distinguishing primary hypothermia from secondary hypothermia.

Indexed as

Cell DeathHypothermiaAnimalsBiomarkersCreatinineMaleRatsRats, WistarBiomarkersCreatinineBiochemical analysisCause of deathForensicHypothermia

Identifiers

PMID40557111
PMCPMC12184468

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.