ArticleOpen veterinary journal2025
Evaluating the safety and functionality of a novel compound containing prebiotics, probiotics, and postbiotics in healthy cats and dogs.
Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Effect of Dietary Postbiotics Derived fromVeterinary sciences · 2026Article
- Probiotic potential of lactic acid bacteria isolated from canine and feline microbiota: functional profiling and host-adapted benefits.Veterinary research communications · 2026Article
- Probiotics as antioxidant, antistress, and growth-enhancing agents in monogastric animals: a narrative review.Frontiers in veterinary science · 2026Review
- A Review of Probiotic Supplementation and Its Impact on the Health and Well-Being of Domestic Cats.Veterinary sciences · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Although various prebiotics, probiotics, and postbiotics are available, their safety and efficacy in combination are unknown. Aim: We investigated the safety and functionality of a newly developed supplement, previously unreported in pet animals, containing 26 types of biotic material bacteria (2 prebiotics, 1 probiotic, and 23 postbiotics) in cats and dogs. The biotic materials included were selected based on current evidence from cats and dogs. Methods: A new supplement developed using species tested in cats and dogs was administered. One-way analysis was used for data obtained from 3 cats (7 days of treatment and 7 days of nontreatment), and a parallel, controlled study was performed in 20 dogs ( Results: In cats, no abnormal values were observed in complete blood count or blood chemistry tests, whereas significant decreases in blood glucose and total cholesterol were confirmed ( Conclusion: The supplement is safe for both cats and dogs. Results of comprehensive analyses suggested that the supplement improved the intestinal environment by regulating the gastrointestinal microbiota.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.