Evidence map›Paper›PMID 40557031›Full record

ArticleCureus2025

Systemic Lupus Erythematosus and Psoriasis Overlap: A Case Series.

Mohannad Ali, Saud Abdullah, Yasameen Abdulhameed, Faisal Elbadawi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohannad AliInternal Medicine, DubaiHealth, Dubai, ARE.
Saud AbdullahInternal Medicine, DubaiHealth, Dubai, ARE.
Yasameen AbdulhameedInternal Medicine, DubaiHealth, Dubai, ARE.
Faisal ElbadawiRheumatology, DubaiHealth, Dubai, ARE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disorder known for its diverse clinical manifestations and potential for overlap with other connective tissue diseases. While overlap syndromes involving conditions such as rheumatoid arthritis (RA) and Sjögren's syndrome (SS) are well established, the coexistence of SLE and psoriasis remains relatively rare and under-reported, despite their distinct immunopathological mechanisms. We present a case series of four female patients diagnosed with both SLE and psoriasis based on expert medical opinion along with supporting biochemical evidence, who experienced complex, relapsing-remitting disease courses. Each case demonstrated unique challenges related to diagnosis, overlapping cutaneous and joint symptoms, and therapeutic management. Overall, we have noted that the use of biological therapy in our patients was effective in terms of clinical remission of psoriasis while avoiding the risk of an SLE flare.

Indexed as

biologicsimmunologyoverlappsoriasissystemic lupus erythematosus

Identifiers

PMID40557031
PMCPMC12185912

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.