ArticleCureus2025
Utilizing Naloxone Education to Reduce the Mortality and Morbidity Rate of Overdose Deaths Within Opioid-Exposed Populations.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWhile efforts are being made to reduce opioid overdose fatalities, there is a need to equip individuals to act in overdose emergencies in an effort to slow the increasing rates of preventable opioid-related deaths in the United States. This study sought to determine whether education on naloxone administration would increase confidence in individuals utilizing harm reduction services to intervene in the presence of an opioid overdose. Methods: A cross-sectional study was conducted that included adult participants attending Challenges, Inc., a mobile harm reduction service site. Participants completed a baseline survey assessing their level of comfort and experience with naloxone administration. An optional standardized educational session focusing on proper naloxone use followed, and all participants were offered free naloxone. Participants completed a post-survey reassessing their confidence and willingness to administer naloxone. Results: Of the 100 participants, 75% reported witnessing at least one opioid overdose, with the majority of those seeing 10 or more opioid overdoses. Additionally, 58% of respondents had previously administered naloxone treatment, on average between one and four times. A significant increase was found in participants' confidence level of administering naloxone following the educational session (p < 0.0001). When asked about the likelihood of intervening when witnessing an opioid overdose, 96% agreed or strongly agreed that they would administer naloxone treatment. Conclusion: A single education session increased the confidence, willingness, and comfort of individuals in administering naloxone in the presence of an opioid overdose. Ultimately, improving naloxone education and access could lead to a decrease in morbidity and mortality in association with opioid-related overdoses.
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Registered trials
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