ArticleCureus2025
Bilateral Pheochromocytoma in a Child Revealing Von Hippel-Lindau Disease.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report the case of a 14-year-old boy admitted with malignant hypertension, headaches, vomiting, and generalized seizures. Clinical, biochemical, and imaging evaluations revealed bilateral adrenal masses with elevated plasma metanephrines, consistent with bilateral pheochromocytoma. After preoperative preparation with an alpha-blocker, the patient underwent right adrenalectomy, and histopathological analysis confirmed a low-aggressive pheochromocytoma. Postoperatively, his blood pressure normalized, catecholamine levels returned to normal, and cardiac function improved. Genetic testing identified a pathogenic variant in the von Hippel-Lindau (VHL) gene, confirming the diagnosis of VHL disease. A 14-month follow-up showed clinical stability, no recurrence, and no additional tumors during systematic screening. This case highlights the importance of early diagnosis and genetic screening in pediatric pheochromocytoma, especially in bilateral cases, to guide treatment and long-term surveillance.
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