Evidence map›Paper›PMID 40556880›Full record

ArticleACS measurement science au2025

Shape-Modified Ultrathin Glass Sheet Cantilever for Precise Single Cell Stiffness Measurement.

Yapeng Yuan, Chaoyang Lyu, Nobutoshi Ota, Ming Li, Cheng Lei, Yoichiroh Hosokawa, Yo Tanaka, Yang Yang, Yaxiaer Yalikun

Abstract read
In one paragraph

Article in ACS measurement science au, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yapeng YuanInstitute of Deep-Sea Science and Engineering, Chinese Academy of Sciences, Sanya 572-0000, China.
Chaoyang LyuDivision of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayamacho, Ikoma, Nara 630-0192, Japan.
Nobutoshi OtaCenter for Biosystems Dynamics Research (BDR), RIKEN, 1-3 Yamadaoka Suita, Osaka 565-0871, Japan.ORCID https://orcid.org/0000-0001-5365-2211
Ming LiSchool of Engineering, Macquarie University, Sydney 2109, Australia.
Cheng LeiThe Institute of Technological Sciences, Wuhan University, Wuhan 430072, China.ORCID https://orcid.org/0000-0001-8439-4235
Yoichiroh HosokawaDivision of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayamacho, Ikoma, Nara 630-0192, Japan.
Yo TanakaCenter for Biosystems Dynamics Research (BDR), RIKEN, 1-3 Yamadaoka Suita, Osaka 565-0871, Japan.
Yang YangInstitute of Deep-Sea Science and Engineering, Chinese Academy of Sciences, Sanya 572-0000, China.
Yaxiaer YalikunDivision of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayamacho, Ikoma, Nara 630-0192, Japan.ORCID https://orcid.org/0009-0007-9362-7193

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to its small size, label-free nature, and excellent compatibility with surrounding instruments, the microcantilever-based sensor is widely used in physical, chemical, and biological measurements. However, traditional microcantilevers face limitations due to complex fabrication methods, intricate operating procedures, or low sensitivity. In this research, we propose a shape-modified, 10 μm ultrathin glass sheet (UTGS)-based cantilever that is highly sensitive (nN/μm) and flexible, integrated with a strain gauge sensor. We present its application in measuring the mechanical properties of single cells. Compared with conventional methods, the proposed UTGS-based cantilever is easier to fabricate, offers superior physical and chemical properties, and demonstrates a high linear correlation between voltage change and applied force or displacement. The cantilever has a sensitivity of 190 nN/μm, making it suitable for measuring the cell stiffness. Additionally, it exhibits excellent optical transparency, enabling real-time observation during measurements, as demonstrated in the stiffness measurement of Dictyostelium cells.

Indexed as

cantilever sensorscell propertycell stiffnessfemtosecond laserultrathin glass sheetYoung’s modulus

Identifiers

PMID40556880
PMCPMC12183576

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.