Evidence map›Paper›PMID 40556825›Full record

Article3 Biotech2025

Evaluating the antioxidant-mediated neuroprotection of hamamelitannin against H₂O₂-induced oxidative damage.

Vishnu Adith Janarthanam, Rupesh Gupta, Alaa S Alhegaili, Ajay Guru, Praveen Kumar Issac

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Comparative Analysis of Polyphenol-Rich Extracts fromMolecules (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vishnu Adith JanarthanamDepartment of Medical Biotechnology, Institute of Biotechnology, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Tamil Nadu, Thandalam, Chennai, 602 105 India.
Rupesh GuptaChitkara University Institute of Engineering and Technology, Chitkara University, Punjab, India.
Alaa S AlhegailiDepartment of Medical Laboratory, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Al-Kharj, 11942 Saudi Arabia.
Ajay GuruDepartment of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.ORCID 0000-0002-8583-9352
Praveen Kumar IssacDepartment of Medical Biotechnology, Institute of Biotechnology, Saveetha School of Engineering, Saveetha Institute of Medical and Technical Sciences, Tamil Nadu, Thandalam, Chennai, 602 105 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Excessive generation of free radicals disrupts redox equilibrium, inducing oxidative stress. Dementia and other related neurodegenerative illnesses are important ailments associated with oxidative stress. Antioxidant treatment proves effective in reducing oxidative stress and associated neurodegeneration. This study examined the therapeutic potential of Hamamelitannin, a hydrolyzable tannin derived from the barks of

Indexed as

AntioxidantHamamelitanninNeuroprotectionOxidative stressReactive oxygen species

Identifiers

PMID40556825
PMCPMC12183148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.