Evidence map›Paper›PMID 40556770›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2024

Hard Negative Sample Mining for Whole Slide Image Classification.

Wentao Huang, Xiaoling Hu, Shahira Abousamra, Prateek Prasanna, Chao Chen

Abstract read
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. A Topological Comparison of the Fluorescence Imitating Brightfield Imaging and H&E Imaging.Topology- and graph-informed imaging informatics : first International Workshop, TGI3 2024, Held in Conjunction with MICCAI 2024, Marrakesh, Morocco, October 10, 2024, Proceedings. International Workshop on Topology- and Graph-Informed ... · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wentao HuangStony Brook University, Stony Brook, NY, USA.
Xiaoling HuHarvard Medical School, Boston, MA, USA.
Shahira AbousamraStony Brook University, Stony Brook, NY, USA.
Prateek PrasannaStony Brook University, Stony Brook, NY, USA.
Chao ChenStony Brook University, Stony Brook, NY, USA.

Funding

DMS/NIGMS 1: Topological Study on Histological Images and Spatial TranscriptomicsR01GM148970 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI CHEN, CHAO, JOHNSON, TRAVIS STEELE · 2022 to 2024
$682k
IMAT-ITCR Collaboration: Combining FIBI and topological data analysis: Synergistic approaches for tumor structural microenvironment explorationR21CA258493 · NCI · STATE UNIVERSITY NEW YORK STONY BROOK · PI CHEN, CHAO, PRASANNA, PRATEEK · 2022 to 2023
$467k
NCI NIH HHS R21 CA258493NIGMS NIH HHS R01 GM148970
6 · The paper itself

Abstract

Weakly supervised whole slide image (WSI) classification is challenging due to the lack of patch-level labels and high computational costs. State-of-the-art methods use self-supervised patch-wise feature representations for multiple instance learning (MIL). Recently, methods have been proposed to fine-tune the feature representation on the downstream task using pseudo labeling, but mostly focusing on selecting high-quality positive patches. In this paper, we propose to mine hard negative samples during fine-tuning. This allows us to obtain better feature representations and reduce the training cost. Furthermore, we propose a novel patch-wise ranking loss in MIL to better exploit these hard negative samples. Experiments on two public datasets demonstrate the efficacy of these proposed ideas. Our codes are available at https://github.com/winston52/HNM-WSI.

Indexed as

Hard Sample MiningSelf-TrainingWhole Slide Image

Identifiers

PMID40556770
PMCPMC12185924

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.