Evidence map›Paper›PMID 40556731›Full record

ArticleFrontiers in chemistry2025

Engineering the mechanical characteristics of regenerated silk fibroin materials: the impact of chemical and physical modification strategies.

Haitao Guan, Fang Ding, Ye Xue, Jinli Zhao

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Haitao Guan *Clinical Innovation Research Center of Nantong University-Nantong Hospital of Traditional Chinese Medicine, Nantong University, Nantong, Jiangsu, China.
Fang Ding *Department of Imaging, Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Nantong, Jiangsu, China.
Ye XueClinical Innovation Research Center of Nantong University-Nantong Hospital of Traditional Chinese Medicine, Nantong University, Nantong, Jiangsu, China.
Jinli ZhaoDepartment of Imaging, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, an in-depth exploration was conducted on the mechanical properties of regenerated silk fibroin (RSF) materials through diverse processing modalities, encompassing wet pressing, humidity treatments at varying levels, and the incorporation of plasticizers. Notably, these approaches induced substantial modifications in the mechanical properties of RSF materials. The elastic strength of RSF exhibited a wide range, from 12.6 to 1,644.8 MPa; the ultimate strength spanned from 0.12 to 42.63 MPa, and the maximum elongation at break fluctuated between 0.67% and 614.38%. Additionally, the mechanisms underlying the effects of these distinct treatment methods were meticulously investigated. This fundamental research not only provides crucial insights into the modulation of silk fibroin's mechanical properties but also holds significant promise for broadening its applications in the biomedical engineering domain, particularly in the pivotal fields of bone tissue and tendon regeneration.

Indexed as

chemical modificationmechanical propertynatural polymerplasticizerregenerated silk fibroin

Identifiers

PMID40556731
PMCPMC12185429

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.