Evidence map›Paper›PMID 40556701›Full record

ArticleRSC advances2025

Multi-target antibacterial Ru-based metallodrugs containing phenylsulfonyl indole derivatives: synthesis and their efficacy against Gram-positive and -negative bacteria.

Shijie Lin, Guangying Yu, Liu Zhang, Xiangwen Liao, Guijuan Jiang, Lianghong Liu

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shijie LinDepartment of Pharmacy, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University) Haikou 570311 China.
Guangying YuSchool of Pharmacy, Jiangxi Science & Technology Normal University Nanchang 330013 China jgjchem@163.com.
Liu ZhangSchool of Pharmacy, Jiangxi Science & Technology Normal University Nanchang 330013 China jgjchem@163.com.
Xiangwen LiaoSchool of Pharmacy, Jiangxi Science & Technology Normal University Nanchang 330013 China jgjchem@163.com.ORCID https://orcid.org/0000-0002-8637-0146
Guijuan JiangSchool of Pharmacy, Jiangxi Science & Technology Normal University Nanchang 330013 China jgjchem@163.com.ORCID https://orcid.org/0000-0002-4491-0431
Lianghong LiuSchool of Pharmaceutical Sciences, Hunan University of Medicine Huaihua 418000 China llhfe@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The escalating crisis of antimicrobial resistance (AMR) underscores the critical need for the development of novel antibacterial drugs with unique mechanisms of action. Herein, a series of phenylsulfonyl indole-modified Ru-based metallodrugs with multi-target antibacterial mechanisms were prepared and evaluated. Notably, all these complexes showed strong bacteriostatic efficacy against

Identifiers

PMID40556701
PMCPMC12184327

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.