ArticleJournal of investigative medicine high impact case reports
Case Report: Two Cases of Kikuchi Disease in West Texas With Non-Self-Limited Disease.
Article in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Kikuchi-Fujimoto disease, also known as histiocytic necrotizing lymphadenitis, is characterized by high fever, lymph node swelling, and leukopenia. It is usually a benign self-limited disease. However, there are reports that it can be associated with other conditions, including infectious and noninfectious processes, autoimmune diseases such as systemic lupus erythematosus (SLE), or even life-threatening conditions like macrophage activation syndrome (MAS). Here, we report 2 cases of Kikuchi disease with non-self-limited disease in West Texas. The first case involves a 13-year-old Hispanic female who presented with prolonged fever for 8 weeks, cervical lymphadenopathy, and malaise. A year later, she was diagnosed with SLE. The second case is a 36-year-old Hispanic female who presented with prolonged fever and cervical, supraclavicular, axillary lymphadenopathy, and pancytopenia. She then developed MAS or hemophagocytic lymphohistiocytosis.
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