ReviewEuropean journal of immunology2025
γδ T Cells and Inborn Errors of Immunity.
Review in European journal of immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- TCR γδ cell-specific STAT5 gain of function induces a druggable chronic human immune dysregulation.Journal of human immunity · 2026Article
- Immunophenotyping, activation, and expansion of gamma delta T cells: flow cytometry profiling andFrontiers in immunology · 2026Review
- What We Know and What We Don't Know About the Function of γδ T Cells.European journal of immunology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gamma delta (γδ) T cells are pivotal in diverse immune responses, encompassing defense against infections, cancer surveillance, and tissue repair. Inborn errors of immunity (IEI) are rare genetic conditions disrupting human immune system development and function, with some impacting γδ T cells. In this review, we focus on IEI leading to a relative increase or decrease of γδ T cells compared to αβ T cells. We discuss how these disorders provide unique insights, in particular concerning the importance of signaling pathways for human αβ versus γδ T cell development, function, and homeostasis. Wherever suitable, we also include data from respective mouse models of IEIs that corroborate patient observations but also illustrate relevant species differences. This comparative approach identifies gaps in knowledge and defines areas for future research. Overall, this review underscores the relevance of IEIs in elucidating the development and function of human γδ T cells with potential implications for diagnosing and treating patients with immune disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.