Evidence map›Paper›PMID 40556135›Full record

ArticleCell transplantation

Adipose-derived mesenchymal stem cell-supported ciprofloxacin therapy effectively protects the kidney parenchyma and functional integrity against acute pyelonephritis damage in rodents.

Chih-Chao Yang, Ya Yue, Pei-Lin Shao, Ben-Chung Cheng, Tsuen-Wei Hsu, Yi-Ling Chen, Sheung-Fat Ko, Hon-Kan Yip, Mel S Lee

Abstract read
In one paragraph

Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chih-Chao YangDivision of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung.
Ya YueThe First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Pei-Lin ShaoDepartment of Nursing, Asia University, Taichung.
Ben-Chung ChengDivision of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung.
Tsuen-Wei HsuDivision of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung.
Yi-Ling ChenDivision of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung.
Sheung-Fat KoDepartment of Radiology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung.
Hon-Kan YipDivision of Cardiology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung.ORCID 0000-0002-6305-5717
Mel S LeeDepartment of Orthopaedic Surgery, Kaohsiung Chang Gung Memorial Hospital, College of Medicine, Chang Gung University, Kaohsiung.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study revealed that adipose-derived mesenchymal stem cell-facilitated ciprofloxacin therapy effectively protected the kidney parenchyma and functional integrity against acute pyelonephritis damage in rodents. In vitro studies revealed that adipose-derived mesenchymal stem cell-derived media significantly suppressed the number of bacterial colony formation units (

Indexed as

Adipose TissueCiprofloxacinKidneyMesenchymal Stem CellsMesenchymal Stem Cell TransplantationPyelonephritisAnimalsFemaleLipopolysaccharidesMaleRatsRats, Sprague-DawleyCiprofloxacinLipopolysaccharidesacute pyelonephritisinflammatory signalingmesenchymal stem cells

Identifiers

PMID40556135
PMCPMC12188078

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.