ArticleBMC geriatrics2025
Effect of deterioration of swallowing functions on the frailty status in older adults: a longitudinal cohort study.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence and influencing factors of oral frailty in cancer patients: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Effects of synergistic tongue and chin resistance training on swallowing function, oral intake, and cognitive function in community-dwelling elderly individuals with frailty: a double-blind randomised controlled trial.Journal of global health · 2025Trial
- Oral Frailty as a Marker of Intrinsic Capacity Decline: A Narrative Review on a Multisystemic Ageing Perspective.Journal of oral rehabilitation · 2026Review
- Dysphagia in hospitalized older patients: the Report-AGE project.European geriatric medicine · 2026Observational
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundDeterioration of swallowing function (DSF) is common among aging adults and can lead to negative health outcomes such as increased risk of malnutrition. However, the longitudinal relationship between the DSF and frailty status remains unclear. This study aimed to investigate whether declining swallowing function is linked to frailty progression in independent older adults.
methodsThis study included 795 community-dwelling Japanese individuals aged ≥ 65 years who participated in two surveys: one at baseline and one after two years. Swallowing function was evaluated using the repetitive saliva swallowing test, tongue pressure test, and questionnaire. DSF was identified by meeting more than one of three criteria: Repeated Saliva Swallow Test below 3, tongue pressure under 27.4 kPa for men and 26.5 kPa for women, and a "yes" response to the questionnaire. Frailty status was assessed using the Kihon Checklist, with participants showing a decline categorized into the "aggravation group." Oral function (number of teeth, occlusal force, masticatory performance, and oral dryness) and physical function (body mass index, gait speed, grip strength, and skeletal muscle mass index) were evaluated. Comparisons between the two groups were made using the Student's t-test or the χ2 test. Differences among the three groups were assessed using the one-way analysis of variance or the χ2 test. Significant differences in continuous variables were analyzed using the Least Significant Difference method, with P-values adjusted using the Bonferroni correction.
resultsInitially, 87 (10.9%) participants were frail. By follow-up, 149 participants (37.9%) had progressed to frailty, 83 of whom (55.7%) exhibited impaired swallowing function at baseline. At baseline, frailty was significantly associated with age, gait speed, decreased swallowing function, number of functional teeth, occlusal force, and masticatory performance. None of the three swallowing function assessment methods were significantly associated with the progression of frailty. In contrast, logistic regression analysis of frailty progression showed that impaired swallowing function was a significant explanatory variable (OR, 1.53; 95% CI: 1.04-2.21).
conclusionThis study found a significant association between frailty and multiple factors, particularly oral function. Specifically, diminished swallowing function has emerged as a notable independent predictor of frailty progression.
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