Evidence map›Paper›PMID 40555999›Full record

ArticleVirology journal2025

Development of a colloidal gold immunochromatographic strip to detect equine infectious anemia virus.

Jianzhong Wang, Jicheng Qiu, Mengmeng Wang, Xiaojie Wu, Xiaoguang Li, Heng Zhang

Abstract readEvaluation Study
In one paragraph

Article in Virology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Rapid serological detection of smoothFrontiers in cellular and infection microbiology · 2026
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jianzhong Wang *Shanxi Key Laboratory for Modernization of TCVM, College of Veterinary Medicine, Shanxi Agricultural University, Taigu, Jinzhong, 030801, China. jianzhongwang@cau.edu.cn.
Jicheng Qiu *Beijing Yuanda Xinghuo Pharmaceutical Technology Co, Beijing, 102615, China.
Mengmeng WangHangzhou Evegen Biotech Co, Ltd., Hangzhou, Zhejiang Province, 310018, China.
Xiaojie WuHangzhou Evegen Biotech Co, Ltd., Hangzhou, Zhejiang Province, 310018, China.
Xiaoguang LiHangzhou Evegen Biotech Co, Ltd., Hangzhou, Zhejiang Province, 310018, China.
Heng ZhangJiangsu Agri-animal Husbandry Vocational College, Taizhou, 225300, China. zhrealm@163.com.

Funding

Central Funds Guiding the Local Science and Technology Development in Shanxi Province YDZJSX2021A034Fund Program for the Scientific Activities of Selected Returned Overseas Professionals in Shanxi Province 20210012the Project of Science and Technology Innovation Fund of Shanxi Agricultural University 2021BQ06the Project of Scientific Research for Excellent Doctors, Shanxi Province, China SXBYKY2021047the Research Fund (Clinical Diagnosis and Treatment of Pet) for Young College Teachers in Ruipeng Commonwealth Foundation RPJJ2020021
6 · The paper itself

Abstract

Equine infectious anemia virus (EIAV) poses a significant global threat to the equine industry, resulting in considerable economic losses and compromised horse health. Given the limited treatment options available, early detection and prevention strategies are essential to combat this viral infection. In this study, we introduce a novel colloidal gold immunochromatographic (ICLF) strip for the rapid and accurate detection of EIAV antibodies. The strip incorporates a unique fusion protein, p26-gp90, designed to enhance both the specificity and sensitivity of the detection method for EIAV antibodies. Through rigorous method validation, our strip has exhibited superior performance compared to existing detection methods. It demonstrates high sensitivity, improved specificity, and excellent stability, enabling reliable and long-term storage. Additionally, the strip allows for fast and precise analysis of clinical samples, making it an invaluable tool for the early detection and prevention of EIAV. The availability of such an accurate and efficient detection method will greatly enhance our ability to combat EIAV by enabling the early identification of infected horses and facilitating effective preventive measures.

Indexed as

Antibodies, ViralChromatography, AffinityEquine Infectious AnemiaGold ColloidInfectious Anemia Virus, EquineAnimalsHorsesReagent StripsSensitivity and SpecificityAntibodies, ViralGold ColloidReagent StripsColloidal gold immunochromatographicEquine infectious anemia virusIn situ diagnosisp26-gp90 fusion protein

Identifiers

PMID40555999
PMCPMC12186446

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.