SynthesisObesity surgery2025
Bariatric Surgery vs. Low-energy Diet and Cardiometabolic Factors: a Systematic Review and Meta-analysis.
Synthesis in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
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Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBariatric surgery and low-energy diets (LED) are established interventions for weight loss and cardiometabolic risk management in individuals with obesity. This systematic review and meta-analysis compares their efficacy in improving cardiometabolic outcomes.
methodsWe performed a systematic search in international databases, including PubMed/MEDLINE, Embase, Scopus, and Web of Science. Cardiometabolic outcomes assessed included cardiovascular disease risk scores, body composition, lipid profiles, glycemic control, and blood pressure.
resultsBariatric surgery showed superior efficacy to LEDs in reducing cardiovascular risk scores (MD - 1.94; 95% CI - 3.48 to - 0.40; p = 0.013) and waist circumference (MD - 0.59 cm; 95% CI - 1.15 to - 0.03; p = 0.040). It significantly improved lipid profiles, with reductions in total cholesterol, LDL, and triglycerides, and increased HDL (all p < 0.05). Glycemic control also improved, with lower fasting glucose, HbA1c, and HOMA-IR (all p < 0.05). Small reductions in blood pressure were noted (p < 0.05). No publication bias was detected, but heterogeneity was significant for triglycerides (p < 0.01).
conclusionsBariatric surgery offers superior and sustained improvements in cardiometabolic health compared to LED, particularly in individuals with higher baseline BMI. These findings support its role as a more effective intervention for long-term risk reduction in individuals with obesity.
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