Evidence map›Paper›PMID 40555929›Full record

ArticleObesity surgery2025

The Influence of Bariatric Surgery on Reproductive Hormones and Ovarian Morphology and Clinical Findings in Women: A Prospective Study.

Yagmur Soykan, Hüseyin Bayhan, Serkan Akogul, Abdulkadir Bedirli

Abstract read
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Article in Obesity surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. The Effects of Bariatric Surgery on Female Fertility: A Narrative Review.International journal of molecular sciences · 2026
    Review
  3. Observational
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yagmur SoykanGazi University, Ankara, Turkey. dr.soykan@hotmail.com.
Hüseyin BayhanGazi University, Ankara, Turkey.
Serkan AkogulPamukkale University, Denizli, Turkey.
Abdulkadir BedirliGazi University, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity in women of reproductive age often causes hormonal imbalances and fertility issues. Bariatric surgery effectively promotes weight loss and metabolic improvement, but its impact on reproductive hormones warrants further investigation. This study examines bariatric surgery's effects on hormonal and clinical changes in women preoperatively and at 3 and 6 months postoperatively.

methodsThis prospective study included 67 women undergoing bariatric surgery. Anthropometric measurements, hormonal profiles, ovarian morphology(via ultrasonography), and the presence of hirsutism and dysmenorrhoea were evaluated preoperatively and at 3- and 6-month follow-ups.

resultsBariatric surgery resulted in significant weight loss and hormonal changes. Body weight (p < 0.001) and BMI (p < 0.001) decreased substantially, with the most rapid reduction occurring in the first 3 months, followed by a slower decline. Androstenedione levels decreased significantly (p < 0.001). Total testosterone levels showed a significant reduction at 6 months (p < 0.001), while SHBG (p < 0.001; p = 0.014), DHEA-S, and AMH (p < 0.001; p < 0.001; p = 0.014) levels increased. No significant changes were observed in FSH and LH levels (p > 0.05). The severity of dysmenorrhea decreased significantly at 6 months (p < 0.001). Additionally, the prevalence of hirsutism (p < 0.001) and polycystic ovary (PCO) morphology (p < 0.001) decreased significantly at 6 months.

conclusionsBariatric surgery significantly decreases testosterone and androstenedione, while increasing AMH, DHEA-S, and SHBG. Improvements in PCO morphology, dysmenorrhea, and hirsutism highlight the effects of bariatric surgery on hormonal balance and reproductive health.

Indexed as

Bariatric SurgeryObesity, MorbidOvaryAdultAndrostenedioneAnti-Mullerian HormoneBody Mass IndexDehydroepiandrosterone SulfateFemaleFollicle Stimulating HormoneFollow-Up StudiesHirsutismHumansLuteinizing HormoneMiddle AgedProspective StudiesAndrostenedioneAnti-Mullerian HormoneDehydroepiandrosterone SulfateFollicle Stimulating HormoneLuteinizing HormoneSex Hormone-Binding GlobulinTestosteroneAdrenal androgensBariatric surgeryDysmenorrheaHirsutismOvarian hormonesPolycystic ovary

Identifiers

PMID40555929
PMCPMC12380637

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.