ReviewWorld journal of microbiology & biotechnology2025
Nucleic acid conjugated gold nanoparticles for biosensing applications: a review.
Review in World journal of microbiology & biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Graphene Oxide (GO) and Gold Nanoparticles (AuNP) Facilitated Electrochemical Biosensing for Lung Cancer Diagnosis.Diagnostics (Basel, Switzerland) · 2026Review
- Beads-on-a-Tip testing for ultrasensitive antigen detection across a large dynamic range.Smart molecules : open access · 2026Article
- L19-Conjugated Gold Nanoparticles for the Specific Targeting of EDB-Containing Fibronectin in Neuroblastoma.Pharmaceutics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gold nanoparticles (AuNPs) have gained widespread use in the development of biosensors for molecular diagnostics due to their ease of functionalization and distinctive optical properties, which are attributed to plasmonic effects. Functionalization strategies are widely applied to manipulate the properties of AuNPs which are then applied for various applications including drug delivery, biosensing, and bioimaging. Among the functionalised AuNPs, nucleic acid-conjugated gold nanoparticles (AuNPs-NA conjugate) have emerged as a powerful platform for biosensing applications due to their unique optical properties, biocompatibility, and ease of functionalization. This review provides an in-depth examination of the integration of nucleic acids with AuNPs for a wide range of biosensing technologies, including detection of pathogens and biomarkers. This review also discusses various methods of conjugating nucleic acids to gold nanoparticles, including covalent bonding, electrostatic interactions, and thiol-based linkages, while highlighting the key factors that influence the stability, specificity, and sensitivity of these conjugates. The paper further explores the optical, electrochemical, and fluorescent biosensing mechanisms enabled by AuNPs-NA conjugates. Finally, it provides a perspective on the future directions of AuNPs-NA conjugates in the development of rapid, cost-effective, and highly sensitive diagnostic tools for clinical and environmental monitoring.
Indexed as
Identifiers
40555853What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.