SynthesisSurgical endoscopy2025
The role of indocyanine green fluorescence angiography in the perioperative period for patients after colorectal surgery: a meta-analysis of propensity score-matched studies with trial sequential analysis.
Synthesis in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Fluorescence-guided surgery in colorectal cancer: current evidence, quantitative advances, and future perspectives.Annals of coloproctology · 2026Review
- Indocyanine green fluorescence angiography in laparoscopic sigmoid and rectal cancer surgery: no reduction in anastomotic leakage but a lower incidence of anastomotic strictures. A prospective single-center study.Frontiers in surgery · 2026Article
- Clinical application of indocyanine green fluorescence imaging technology in laparoscopic rectal cancer surgery.Journal of gastrointestinal oncology · 2025Article
- Gastrointestinal endoscopy and visceral surgery: current status and potentials for interdisciplinary patient care.Therapeutic advances in gastrointestinal endoscopyReview
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe utilization of Indocyanine Green (ICG) Fluorescence Angiography (FA) in colorectal surgery is gaining increasing traction. This manuscript employs meta-analysis, propensity score-matched (PSM), and trial sequential analysis (TSA) to compare the perioperative outcomes between colorectal cancer patients who underwent surgery with and without ICG FA. MATERIALS AND
methodsA thorough literature search was conducted across many databases, including PubMed, Embase, Cochrane Library, and Web of Science, from the foundation of each database to November 2024. The quality of the included studies was evaluated using the Newcastle-Ottawa Scale. Meta-analysis was conducted utilizing R language software. The I
resultsA total of 25 studies involving 6877 patients were analyzed, and all utilized PSM. Analysis of the results showed that compared with the Non-ICG group (control group), the ICG group had a low rate of anastomotic leakage (OR 0.50, 95% CI 0.42 to 0.61, P < 0.05), symptomatic anastomotic leakage (OR 0.32, 95% CI 0.21 to 0.49, P < 0.05), total postoperative complications (OR 0.79, 95% CI 0.66 to 0.95, P = 0.01), and reoperation (OR 0.33, 95% CI 0.17 to 0.65, P < 0.05), and a shorter mean postoperative hospital stay (MD - 0.91, 95% CI - 1.41 to - 0.41, P < 0.05).
conclusionICG FA significantly reduces the incidence of anastomotic leaks, symptomatic anastomotic leaks, total postoperative complications, and the need for reoperation while decreasing postoperative hospital stay.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.