Evidence map›Paper›PMID 40555768›Full record

ReviewCardiovascular and interventional radiology2025

Beyond the Scalpel: the Role of Image-Guided Thermal Ablation in Management of Metastatic Renal Cell Carcinoma in the Era of Immunotherapy.

Kin Fen Kevin Fung, Philippe Barthelemy, Fabien Moinard-Butot, Mathilde Airoldi, Roberto Luigi Cazzato, Afshin Gangi

Abstract readReview
In one paragraph

Review in Cardiovascular and interventional radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kin Fen Kevin FungDepartment of Radiology, Hong Kong Children's Hospital, Kowloon, Hong Kong.ORCID http://orcid.org/0000-0002-2731-2915
Philippe BarthelemyDepartment of Medical Oncology, University Hospital of Strasbourg, 1, Place de L'hopital, 67000, Strasbourg, France.
Fabien Moinard-ButotDepartment of Medical Oncology, University Hospital of Strasbourg, 1, Place de L'hopital, 67000, Strasbourg, France.
Mathilde AiroldiDepartment of Medical Oncology, Institut de Cancérologie Strasbourg Europe, Strasbourg, France.
Roberto Luigi CazzatoDepartment of Interventional Radiology, University Hospital of Strasbourg, 1, Place de L'hopital, 67000, Strasbourg, France.
Afshin GangiDepartment of Interventional Radiology, University Hospital of Strasbourg, 1, Place de L'hopital, 67000, Strasbourg, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma (RCC) is the most common type of kidney cancer and accounts for approximately 90% of all renal malignancies. About 30% of patients have metastatic disease at their initial presentation. Historically, these patients have very poor prognosis with a median survival of 12 months. The recent introduction of immune checkpoint inhibitors (ICI)-based immunotherapy, which disrupts cancer-induced immune tolerance and promotes immune-mediated cancer cell killing, has significantly improved patient outcome. While ICI-based therapy represents the standard of care for metastatic RCC, there are significant treatment-related adverse effects. This review article will examine how image-guided ablation, as an adjunct to immunotherapy, can improve survival and quality of life in patients with metastatic RCC.

Indexed as

Ablation TechniquesCarcinoma, Renal CellImmunotherapyKidney NeoplasmsHumansImmune Checkpoint InhibitorsQuality of LifeImmune Checkpoint InhibitorsCryoablationImmunotherapyMetastasisRenal cell carcinomaThermal Ablation

Identifiers

PMID40555768
PMCPMC12325399

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.