Evidence map›Paper›PMID 40555648›Full record

ReviewJournal of gastroenterology and hepatology2025

Carcinoma of Esophagus.

Joseph Sung, Dongxin Lin, Rebecca Fitzgerald, Prateek Sharma, Simon Law, David Ilson

Abstract readReview
In one paragraph

Review in Journal of gastroenterology and hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Radiology and oncology · 2026
    Article
  3. Esophageal cancer: from pathogenesis to precision therapies.Signal transduction and targeted therapy · 2026
    Review
  4. Review
  5. Review
  6. Carcinoma of Esophagus.Journal of gastroenterology and hepatology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joseph SungLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.ORCID https://orcid.org/0000-0003-3125-5199
Dongxin LinSun Yat-sen University Cancer Center, Sun Yat-sen University, Guangzhou, China.
Rebecca FitzgeraldEarly Cancer Institute, University of Cambridge, Cambridge, UK.
Prateek SharmaSchool of Medicine, University of Kansas, Kansas, USA.
Simon LawDepartment of Surgery, School of Clinical Medicine, University of Hong Kong, Hong Kong.
David IlsonGastrointestinal Oncology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Carcinoma of esophagus is one of the most common cancer worldwide, but its epidemiology is changing. Squamous cell carcinoma is declining in the East, but adenocarcinoma is rising in the West, probably related to the pandemic of obesity and changing lifestyle. Screening of esophageal cancer (both endoscopic and nonendoscopic methods) is recommended in patients suffering from long-term acid reflux symptoms associated with high-risk factors and surveillance in patients with Barrett's esophagus. Endoscopy with virtual chromoendoscopy, endoscopic ultrasound, and CT scan is essential for diagnosis and staging of the disease. Endoscopic therapy can be used to treat early diseases. Surgery remains a mainstay treatment. Multimodality treatment strategies involving combinations of chemotherapy, radiotherapy, and more recently immunotherapy and target therapies are gaining momentum.

Indexed as

AdenocarcinomaCarcinoma, Squamous CellEsophageal NeoplasmsBarrett EsophagusCombined Modality TherapyEarly Detection of CancerEsophagoscopyGastroesophageal RefluxHumansNeoplasm StagingRisk Factors

Identifiers

PMID40555648
PMCPMC12315794

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.