Evidence map›Paper›PMID 40555517›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

Purkinje Cell Spatial Correlation Dynamics Are Key to Cerebellar Cortical Contributions to Behavior.

Martha L Streng, Russell E Carter, Benjamin W Kottke, Kayla Togneri, Emma Wasserman, Vijay Rajendran, Suhasa B Kodandaramaiah, Esther Krook-Magnuson, Timothy J Ebner

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Martha L StrengDepartments of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455 stren021@umn.edu.
Russell E CarterDepartments of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455.
Benjamin W KottkeDepartments of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455.
Kayla TogneriDepartments of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455.
Emma WassermanDepartments of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455.
Vijay RajendranMechanical Engineering, University of Minnesota, Minneapolis, Minnesota 55455.
Suhasa B KodandaramaiahMechanical Engineering, University of Minnesota, Minneapolis, Minnesota 55455.ORCID 0000-0002-7767-2644
Esther Krook-MagnusonDepartments of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455.ORCID 0000-0002-6119-0165
Timothy J EbnerDepartments of Neuroscience, University of Minnesota, Minneapolis, Minnesota 55455.ORCID 0000-0001-8464-3860

Funding

Viral Innovation CoreP30DA048742 · NIDA · UNIVERSITY OF MINNESOTA · PI TIMOTHY J EBNER · 2020 to 2026
$19.0M
Predoctoral Training of NeuroscientistsT32NS105604 · NINDS · UNIVERSITY OF MINNESOTA · PI A DAVID REDISH · 2018 to 2026
$3.5M
Hippobellum: Cerebellar influence on the hippocampus and temporal lobe seizuresR01NS112518 · NINDS · UNIVERSITY OF MINNESOTA · PI Esther Krook-Magnuson · 2020 to 2026
$3.4M
Miniaturized head-mounted device for pan-cortical electro-optical activity monitoringR01NS111028 · NINDS · UNIVERSITY OF MINNESOTA · PI KODANDARAMAIAH, SUHASA B, SWISHER, SARAH L · 2019 to 2023
$2.4M
Cerebellar computations in health and epilepsyR00NS121274 · NINDS · UNIVERSITY OF MINNESOTA · PI Martha L Streng · 2024 to 2026
$715k
Cerebellar computations in health and epilepsyK99NS121274 · NINDS · UNIVERSITY OF MINNESOTA · PI STRENG, MARTHA L · 2022 to 2023
$226k
NIDA NIH HHS P30 DA048742NINDS NIH HHS K99 NS121274NINDS NIH HHS R00 NS121274NINDS NIH HHS R01 NS111028NINDS NIH HHS R01 NS112518NINDS NIH HHS T32 NS105604
6 · The paper itself

Abstract

A major challenge in cerebellar physiology is determining how the stereotypic, conserved circuitry of the cerebellar cortex, with its dominant parasagittal and transverse architectures, underlies its fundamental computations and contributions to behavior. Recent advances have allowed for the resolution of Purkinje cell dendritic activity at large scales, but the full roles of these Purkinje cell dynamics during behavior remain undetermined. To interrogate Purkinje cell dynamics at the population level during behavior, we implemented a novel approach for awake, chronic, wide-field Ca

Indexed as

Behavior, AnimalCerebellar CortexPurkinje CellsAnimalsCalciumCations, DivalentDendritesFemaleMaleMiceMice, TransgenicMolecular ImagingNerve NetOptical ImagingSpatial AnalysisCalciumCations, DivalentCalcium imagingcerebellummesoscale imagingPurkinje cellspatial independent component analysis

Identifiers

PMID40555517
PMCPMC12311771

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.