ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025
Emerging Adulthood Is Marked by a Cortical Dendritic Arborization Phase Depending on the Actin Nucleator Cobl.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Puberty triggers significant changes. However, besides the pruning of synapses, little is known about more long-range alterations during brain maturation. Actin filament formation-a process ignited by actin nucleators-is crucial for life and also a driving force behind cellular morphology changes. Yet, the physiological importance of especially the more recently discovered, evolutionary younger actin nucleators largely remains elusive. We demonstrate the consequences of deficiency for the actin nucleator Cobl in the mouse brain. We identify remarkably layer- and age-restricted cortical
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