Evidence map›Paper›PMID 40555441›Full record

ArticleBMJ open2025

Evaluation of the outpatient parenteral antimicrobial therapy (OPAT) service in Malaysian public hospitals: a mixed-methods study protocol.

Audrey Huili Lim, Norazida Ab Rahman, Afra Nahdia Marizan Nor, Nor Arisah Misnan, Peter Seah Keng Tok

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Audrey Huili LimInstitute for Clinical Research, National Institutes of Health, Ministry of Health Malaysia, Shah Alam, Malaysia audreylim@moh.gov.my.ORCID http://orcid.org/0000-0001-6721-1505
Norazida Ab RahmanInstitute for Clinical Research, National Institutes of Health, Ministry of Health Malaysia, Shah Alam, Malaysia.
Afra Nahdia Marizan NorPharmacy Department, Hospital Sungai Buloh, Sungai Buloh, Malaysia.
Nor Arisah MisnanMedical Department, Hospital Sungai Buloh, Sungai Buloh, Malaysia.
Peter Seah Keng TokInstitute for Clinical Research, National Institutes of Health, Ministry of Health Malaysia, Shah Alam, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOutpatient parenteral antimicrobial therapy (OPAT) is an innovative approach to manage infections that require extended courses of intravenous antibiotics by enabling patients to receive treatment in an outpatient setting. In Malaysia, there has yet to be a systematic evaluation of the OPAT service. This study aims to describe the safety, clinical indications and treatment outcomes of the OPAT service in Malaysia, assess patients' satisfaction and experiences and determine the facilitators and barriers associated with the provision of the OPAT service in Malaysia. METHODS AND ANALYSIS: A mixed-methods approach combining qualitative and quantitative methods will be employed for a comprehensive understanding of the provision of the OPAT service in Malaysian public hospitals. The study consists of four distinct parts: systematic review, retrospective cohort analysis of clinical outcomes, patients' satisfaction survey and focus group discussions on providers' experiences. A longitudinal analysis of the clinical outcomes (treatment success/failure, infection cure, adverse events, readmission and mortality) of the OPAT patients' cohort will be conducted using descriptive and conclusive statistics, in addition to rates of patients' satisfaction and evaluation of providers' experiences. ETHICS AND DISSEMINATION: This study is registered in the National Medical Research Register (NMRR ID-24-00941-2C8) and approved by the Medical Research and Ethics Committee, Ministry of Health Malaysia (Ref: 24-00941-2C8). Written informed consent will be obtained from all participants. The results will be submitted for publication in a peer-reviewed journal and presented at one or more scientific conferences.

Indexed as

Ambulatory CareAnti-Bacterial AgentsAnti-Infective AgentsHospitals, PublicHumansInfusions, ParenteralMalaysiaPatient SatisfactionResearch DesignRetrospective StudiesSystematic Reviews as TopicTreatment OutcomeAnti-Bacterial AgentsAnti-Infective AgentsAntibioticsHospital to Home TransitionINFECTIOUS DISEASESProtocols & guidelines

Identifiers

PMID40555441
PMCPMC12198778

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.