Evidence map›Paper›PMID 40555173›Full record

ArticleDevelopmental cell2025

Facing up to your potential: Neural crest under the influence of TGF-β.

Mary E Swartz, Johann K Eberhart

Abstract readComment
In one paragraph

Article in Developmental cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mary E SwartzDepartment of Molecular Biosciences, Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, TX 78712, USA.
Johann K EberhartDepartment of Molecular Biosciences, Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, TX 78712, USA. Electronic address: eberhart@austin.utexas.edu.

Funding

Mechanisms underlying the multifaceted basis of craniofacial dysmorphogenesisR35DE029086 · NIDCR · UNIVERSITY OF TEXAS AT AUSTIN · PI JOHANN K EBERHART · 2019 to 2026
$7.6M
Genetic Screens in Zebrafish to Identify Gene-Ethanol InteractionsR01AA023426 · NIAAA · UNIVERSITY OF TEXAS AT AUSTIN · PI JOHANN K EBERHART · 2015 to 2026
$3.0M
Characterizing the Genetics of FASD in Complementary Mouse and Fish ModelsR01AA031346 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JOHANN K EBERHART, Scott Parnell · 2023 to 2026
$2.2M
NIAAA NIH HHS R01 AA023426NIAAA NIH HHS R01 AA031346NIDCR NIH HHS R35 DE029086
6 · The paper itself

Abstract

Neural crest cells, an ectoderm derivative, give rise to a variety of cell types. Only in cephalic regions do these cell types include bone and cartilage, which are mesodermal derivatives elsewhere. In this issue of Developmental Cell, Rothstein et al. show that TGF-β signaling combined with low Wnt signaling expands the potential of cranial neural crest cells to become skeletal elements.

Indexed as

Neural CrestTransforming Growth Factor betaAnimalsCell DifferentiationHumansSignal TransductionWnt Signaling PathwayTransforming Growth Factor beta

Identifiers

PMID40555173
PMCPMC13182822

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.