Evidence map›Paper›PMID 40554744›Full record

ArticlePLoS biology2025

The aging ovary stands on the shoulders of giant multinucleated cells.

Avery A Ahmed, Stephanie A Pangas

Abstract readComment
In one paragraph

Article in PLoS biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Avery A AhmedDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, United States of America.
Stephanie A PangasDepartment of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, United States of America.ORCID 0000-0001-5748-5844

Funding

Comprehensive Mechanisms in Reproductive SciencesT32HD098068 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI STEPHANIE A. PANGAS · 2020 to 2026
$2.4M
NICHD NIH HHS T32 HD098068
6 · The paper itself

Abstract

Reproductive aging is associated with declining fertility and increasing inflammation, though these events are not well understood. An exciting new study in PLOS Biology utilizes cutting-edge technologies to characterize the role of multinucleated giant cells in ovarian aging.

Indexed as

AgingGiant CellsOvaryAnimalsFemaleHumans

Identifiers

PMID40554744
PMCPMC12187170

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.