ArticlePLOS global public health2025
From need to neglect: Exploring psychological barriers to preventive interventions in pregnancy.
Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Assessment of Nutritional and Nonnutritional Correlates of Anemia in Pregnancy: A Hospital-Based Cross-Sectional Study for Public Health Interventions in the Bono East Region of Ghana.Health science reports · 2026Article
- Drivers of trimester disparities in asymptomatic malaria during pregnancy in Kintampo South District: evidence from an Oaxaca-Blinder decomposition Analysis.BMC public health · 2026Article
- Barriers to compliance with hepatitis B vaccination: sociocultural and socioeconomic perspectives of pregnant women in the Bono East Region of Ghana.BMC pregnancy and childbirth · 2026Article
- Hypertension among incarcerated individuals in the Ashanti Region of Ghana: examining prevalence and correlates based on the Social Cognitive Theory.BMC public health · 2026Article
- Perinatal depression and anxiety in Ghana: a qualitative study of women's perspectives on AI-driven interventions.BMC pregnancy and childbirth · 2025Article
- Article
- Prevalence and Correlates of Hepatitis B in Pregnancy: Evidence From a Cross-Sectional Study in Bono East Region, Ghana.Health science reports · 2025Article
- Maternal immunisation towards prevention of neonatal tetanus: insights from a cross-sectional study in Pru East Municipality, Ghana.BMJ public health · 2025Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To effectively reduce the impact of hepatitis B and malaria during pregnancy, consistent adherence to key preventive interventions such as vaccination, the use of long-lasting insecticidal nets (LLINs), and the administration of Sulfadoxine-Pyrimethamine (SP) is essential. Achieving high coverage of these interventions, however, requires a clear understanding of the factors that hinder compliance. Therefore, this study investigated the psychological determinants of non-compliance with these interventions among pregnant women in the Bono East Region. A prospective cross-sectional mixed-method study was conducted among 1,430 pregnant women. Data were collected through serological screening, questionnaires, in-depth interviews, and focus group discussions. Quantitative analysis included descriptive statistics, Chi-square tests, and logistic regression with results shown as crude and adjusted odds ratios at 95% confidence intervals. The quantitative analysis involved a four-step thematic analysis with a focus on transcription, profiling, coding, and thematic framework. The study revealed a series of psychological barriers to compliance. The fear of side effects (AOR = 2.17; 95% CI: 1.78 - 4.06), forgetfulness (AOR = 6.02; 95% CI: 2.13 - 9.91), and pain (AOR = 2.95; 95% CI: 1.97 - 4.94) increased the odds of hepatitis B infection. Likewise, fear of side effects (AOR = 2.07; 95% CI: 1.66 - 3.72), absence of symptoms (AOR = 1.82; 95% CI: 1.53 - 2.26), forgetfulness (AOR = 2.41; 95% CI: 1.48 - 3.90), perceived efficacy of herbs (AOR = 2.35; 95% CI: 1.49 - 3.68), pain (AOR = 2.52; 95% CI: 1.48 - 4.27), uncertainty (AOR = 2.38; 95% CI: 1.48 - 3.84), and prolonged adherence (AOR = 1.71; 95% CI: 1.10 - 2.66) increased the odds of malaria. The identified barriers and their strong association with increased odds of infections call for a groundbreaking and policy-driven public health response. Consequently, integrating psychosocial support and mental health services into antenatal care could play a crucial role in overcoming these barriers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.