ArticlePloS one2025
Organizational barriers in HPV vaccination uptake: A cross-sectional study among health sciences students.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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Who cites it
3 citing papers in PubMed.
- Trends, disparities, and multilevel interventions: A global review of HPV vaccination among university students.Human vaccines & immunotherapeutics · 2026Review
- Association Between HPV Vaccination and Cervical Dysplasia Severity in HPV-Positive Women.Diagnostics (Basel, Switzerland) · 2026Article
- Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHuman papillomavirus (HPV) is a leading cause of cervical, anal, and oropharyngeal cancers. Despite the proven effectiveness of HPV vaccination, uptake remains low, particularly among males and specific demographic groups. In Italy, national HPV vaccination coverage stagnated at 38.8% in 2022, with significant regional disparities. While previous studies have explored individual and cultural barriers, organizational challenges within academic institutions remain underexamined. The aim of this cross-sectional study was assessing the uptake of HPV vaccination among Health Sciences students at the University of Naples Federico II.
methodsAn anonymous online survey collected data on demographics, vaccination status, and institutional barriers. Logistic regression models were used to identify predictors of vaccination, adjusting for demographic factors, institutional communication, and knowledge-attitude scores.
resultsAmong 354 participants, 55.1% reported receiving at least one HPV vaccine dose. Female students had significantly higher vaccination rates (aOR: 7.95; 95% CI: 4.24-14.90), while older age was associated with lower uptake (aOR: 0.81; 95% CI: 0.73-0.91). Institutional vaccination invitations increased the likelihood of vaccination nearly threefold (aOR: 2.81; 95% CI: 1.48-5.33). Attitudes toward vaccination strongly predicted uptake, whereas knowledge scores showed no significant association.
conclusionsThese findings highlight the need for structured institutional interventions, including targeted education, proactive vaccination invitations, and improved access to on-campus vaccination services. Strengthening university-led initiatives could significantly enhance HPV vaccine uptake among future healthcare professionals, contributing to broader public health efforts in HPV-related cancer prevention.
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