Evidence map›Paper›PMID 40554225›Full record

ArticleEnvironment international2025

Long-term exposure to air pollution and risk of dementia among older individuals of a Danish nationwide administrative cohort.

Zorana J Andersen, Youn-Hee Lim, Jiawei Zhang, Stéphane Tuffier, Thomas Cole-Hunter, Marie Bergmann, Steffen Loft, Laust H Mortensen, Jie Chen, Massimo Stafoggia and 18 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environment international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Environmental Pollution, Biomarkers, and Dementia: An Evidence Review.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Zorana J AndersenSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Youn-Hee LimSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Jiawei ZhangSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Stéphane TuffierSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Thomas Cole-HunterSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Marie BergmannSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Steffen LoftSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Laust H MortensenSection of Epidemiology, Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Denmark Statistics, Copenhagen, Denmark.
Jie ChenInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands; Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Massimo StafoggiaDepartment of Epidemiology, Lazio Region Health Service/ASL Roma 1, Rome, Italy; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Kees de HooghSwiss Tropical and Public Health Institute, Allschwil, Switzerland; University of Basel, Basel, Switzerland.
Klea KatsouyanniDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece; Environmental Research Group, School of Public Health, Imperial College London, London, UK.
Danielle VienneauSwiss Tropical and Public Health Institute, Allschwil, Switzerland; University of Basel, Basel, Switzerland.
Sophia RodopoulouDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Evangelia SamoliDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Mariska BauwelinckBrussels Institute for Social and Population Studies (BRISPO), Vrije Universiteit Brussel, Brussels, Belgium.
Jochem O KlompmakerNational Institute for Public Health and the Environment, Bilthoven, the Netherlands; Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Richard AtkinsonPopulation Health Research Institute, St George's University of London, London, UK.
Nicole A H JanssenNational Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Bente OftedalDepartment of Air Quality and Noise, Norwegian Institute of Public Health, Oslo, Norway.
Matteo RenziDepartment of Epidemiology, Lazio Region Health Service/ASL Roma 1, Rome, Italy.
Francesco ForastiereDepartment of Epidemiology, Lazio Region Health Service/ASL Roma 1, Rome, Italy; Environmental Research Group, School of Public Health, Imperial College London, London, UK.
Maciek StrakInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands; National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Lau C ThygesenNational Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.
Paola ZaninottoDepartment of Epidemiology and Public Health, University College London, London, UK.
Bert BrunekreefInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands.
Gerard HoekInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands.
Rina SoSection of Environmental Health, Department of Public Health, University of Copenhagen, Copenhagen, Denmark; Department of Epidemiology and Public Health, University College London, London, UK. Electronic address: rina.so@sund.ku.dk.

Funding

Integrting Information About Aging SurveysR01AG030153 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sara Adar, Alden L. Gross · 2007 to 2026
$41.7M
NIA NIH HHS R01 AG030153
6 · The paper itself

Abstract

backgroundIncreasing evidence associates air pollution with dementia, but some pollutants and susceptible groups are understudied.

methodsWe followed all Danish residents aged ≥60 years as of 1-1-2000, without prior dementia, until 12-31-2018 for dementia incidence identified via hospital contact or prescription. We assessed annual mean levels of fine particulate matter (PM

findingsAmong 934,792 individuals, 81,731 developed dementia over a mean follow-up of 11·6 years. Mean levels of PM DISCUSSION: Even low levels of air pollution in Denmark were associated with dementia development, especially among certain susceptible groups, emphasizing the need for targeted intervention strategies.

Indexed as

Air PollutantsAir PollutionDementiaEnvironmental ExposureAgedAged, 80 and overCohort StudiesDenmarkFemaleHumansIncidenceMaleMiddle AgedNitrogen DioxideParticulate MatterProportional Hazards ModelsAir PollutantsNitrogen DioxideParticulate MatterSootAdministrative cohortAir pollutionDementiaDenmarkIncidenceLong-term exposure

Identifiers

PMID40554225
PMCPMC12536445

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.