Evidence map›Paper›PMID 40553291›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2025

Bioluminescent Imaging of Patient-Derived Brain Tumors in Live Mice.

Dillon McKenna, Chitra Venugopal, Sheila K Singh

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dillon McKennaCentre for Discovery in Cancer Research, McMaster University, Hamilton, ON, Canada.
Chitra VenugopalCentre for Discovery in Cancer Research, McMaster University, Hamilton, ON, Canada.
Sheila K SinghCentre for Discovery in Cancer Research, McMaster University, Hamilton, ON, Canada. ssingh@mcmaster.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patient-derived tumor xenograft (PDX) models are crucial for understanding brain tumor progression and for pre-clinical evaluation of therapeutic interventions. Luciferase-based bioluminescence imaging offers a non-invasive approach to visualizing and quantifying tumor development across multiple time points. This chapter presents a methodology for employing the IVIS® (in vivo imaging) system to analyze tumor dynamics in luciferase expressing PDX brain tumor models.

Indexed as

Brain NeoplasmsLuminescent MeasurementsAnimalsDisease Models, AnimalGenes, ReporterHumansLuciferasesMiceXenograft Model Antitumor AssaysLuciferasesBioluminescenceBrain tumorIVIS® Spectrum In Vivo Imaging SystemPatient derived xenograftQuantificationTumor progression

Identifiers

PMID40553291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.