Evidence map›Paper›PMID 40553116›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

First-in-human PET neuroimaging of [

Emily Murrell, Lucas Narciso, Kimberly L Desmond, Caitlin Chow, Anton Lindberg, Armando Garcia, Chester A Mathis, Samuel Svensson, Antonio P Strafella, Neil Vasdev

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Association of [Neurology · 2026
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emily Murrell *Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Lucas Narciso *Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Kimberly L DesmondBrain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Caitlin ChowBrain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Anton LindbergBrain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Armando GarciaBrain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada.
Chester A MathisDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA, USA.
Samuel SvenssonOxiant Discovery, Södertälje, SE-15136, Sweden.
Antonio P StrafellaBrain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada. antonio.strafella@uhn.ca.
Neil VasdevBrain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, ON, Canada. neil.vasdev@utoronto.ca.ORCID 0000-0002-2087-5125

Funding

Azrieli Foundation Azrieli FoundationCanada Foundation for Innovation JELFCanada Research Chairs Tier-1CIHR PJT-173540CurePSP CurePSPKrembil Foundation Krembil FoundationMichael J. Fox Foundation for Parkinson's Research MJFF-024347 & MJFF-024348Ontario Research Foundation JELFRossy Foundation Rossy FoundationTau Consortium Tau Consortium
6 · The paper itself

Abstract

purposeThis first-in-human positron emission tomography (PET) study evaluates [

methodsSynthesis of [

results[

conclusions[

Indexed as

BenzothiazolesBrainNeuroimagingPositron-Emission TomographyRadiopharmaceuticalsAgedFemaleFluorine RadioisotopesHumansMaleMiddle AgedBenzothiazolesFluorine RadioisotopesRadiopharmaceuticals[18F]OXD-2314Alzheimer’s diseaseFirst-in-humanPETTau

Identifiers

PMID40553116
PMCPMC12660345

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.