Evidence map›Paper›PMID 40553010›Full record

ArticleClinical and experimental dental research2025

The Influence of Deep Margin Elevation and Immediate Dentin Sealing on the Fracture Strength of Premolars Restored With Indirect Inlays: An In Vitro Study.

Lulwa E Al-Turki, Osamah A Alsulimani, Khadijah M Baik, Haytham Othmani, Naif M Alqarni, Abdullah A Alqarni, Raghad A Al-Dabbagh

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Article in Clinical and experimental dental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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3 · Its place in the literature

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1 citing paper in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Lulwa E Al-TurkiDepartment of Oral Maxillofacial Prosthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah, Makkah Province, Saudi Arabia.ORCID 0000-0002-9286-488X
Osamah A AlsulimaniDepartment of Oral Diagnostic Sciences, Faculty of Dentistry, King Abdulaziz University, Jeddah, Makkah Province, Saudi Arabia.ORCID 0000-0003-0922-2868
Khadijah M BaikDepartment of Oral Maxillofacial Prosthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah, Makkah Province, Saudi Arabia.ORCID 0000-0002-9863-9501
Haytham OthmaniChoueifat Medical Center, Jeddah, Makkah Province, Saudi Arabia.
Naif M AlqarniAl-Rahaily medical Center, Jeddah, Makkah Province, Saudi Arabia.
Abdullah A AlqarniPeriodontics Resident, King Fahad General hospital, Jeddah, Makkah Province, Saudi Arabia.
Raghad A Al-DabbaghDepartment of Oral Maxillofacial Prosthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah, Makkah Province, Saudi Arabia.ORCID 0000-0003-2610-9592

Funding

This study was funded from King Abdulaziz University, General Program (G: 508-165-1439).
6 · The paper itself

Abstract

objectiveTo evaluate the effect of deep margin elevation (DME) and immediate dentin sealing (IDS) on the fracture strength of premolars restored with lithium disilicate inlay restorations. MATERIALS AND

methodsStandard MOD inlays with proximal box preparations extending 3 mm apical to the cementoenamel junction were prepared on forty sound premolars (n = 10) randomly divided into four groups: inlays without DME and without IDS (G1); inlays without DME but with IDS (G2); inlays with DME but without IDS (G3); and inlays with both techniques applied (G4). Composite resin was applied incrementally to elevate the proximal cervical margin coronally to the cementoenamel junction. For immediate dentin sealing, bonding agent was applied immediately after tooth preparation. All teeth were restored with lithium disilicate inlays and, after adhesive resin cementation, specimens were thermomechanically aged for 500 cycles at 5°-55°C and then subjected to load failure testing. Failure loads and locations were recorded and analyzed using one- and two-way ANOVA with Tukey's post-hoc testing (α = 0.05). Failure modes were analyzed using descriptive statistics.

resultsThe mean fracture loads were 565.76 ± 233.22 N, 978.47 ± 394.2 N, 974.31 ± 334.7 N, and 1108.21 ± 292.41 N for G1, G2, G3, and G4, respectively. Deep margin elevation (p = 0.011) and immediate dentin sealing (p = 0.010) were associated with significantly increased fracture loads. Fracture loads were significantly lower for G1 teeth than for G2-G4 teeth, but there were no significant differences between G2, G3, and G4. G1 teeth showed 50% catastrophic and non-catastrophic failures, which increased to 60% for G2 and decreased to 20% for G3 teeth. Samples with both seals and elevation (G4) had a 60% catastrophic failure rate.

conclusionsWhen applied individually or together, deep margin elevation and immediate dentin sealing significantly increase the fracture strength of premolars restored with indirect lithium disilicate inlays. CLINICAL IMPLICATIONS: In the challenging setting of margin elevation, studies on the effects of immediate dentin sealing have generally been limited to evaluating marginal integrity and bond strength. The findings of this In Vitro study suggest that both deep margin elevation and immediate dentin sealing protocols are likely to improve clinical outcomes of indirect lithium disilicate inlay restorations and may be considered viable options in clinical practice.

Indexed as

BicuspidDentinInlaysTooth FracturesComposite ResinsDental BondingDental PorcelainDental Restoration FailureDental Stress AnalysisDentin-Bonding AgentsHumansIn Vitro TechniquesComposite ResinsDental PorcelainDentin-Bonding Agentslithia disilicatedeep margin elevationdentin sealingfracture strengthlithium disilicate inlay restorations

Identifiers

PMID40553010
PMCPMC12186461

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.