Evidence map›Paper›PMID 40552809›Full record

ReviewJournal of bacteriology2025

Recent advances in mycobacterial transcription: insights beyond the general pathway.

Nilanjana Hazra, Jayanta Mukhopadhyay

Abstract readReview
In one paragraph

Review in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nilanjana HazraDepartment of Chemical Sciences, Bose Institute, Kolkata, West Bengal, India.ORCID 0009-0001-1569-7491
Jayanta MukhopadhyayDepartment of Chemical Sciences, Bose Institute, Kolkata, West Bengal, India.ORCID 0000-0002-2948-5908

Funding

Bose Institute INTRAMURAL GRANT
6 · The paper itself

Abstract

The conventional idea of prokaryotic transcription represents a collection of pathways assembled from disparate studies across diverse bacterial species. This cumulative approach, though reveals core-conserved mechanisms, likely excludes the transcriptional pathways unique to an organism. The understanding of mycobacterial transcription suffers from such generalizations as its extreme GC bias, complex RNA polymerase (RNAP), abundance of short transcripts predominating its transcriptome, extensive σ factor utilization, and a constant battle against host stress implicates a distinct transcriptional landscape. This review highlights specific insights into mycobacterial RNAP architecture, promoter recognition, and elongation dynamics, against the general comprehensive narration of bacterial transcription.

Indexed as

Gene Expression Regulation, BacterialMycobacteriumTranscription, GeneticBacterial ProteinsDNA-Directed RNA PolymerasesPromoter Regions, GeneticSigma FactorBacterial ProteinsDNA-Directed RNA PolymerasesSigma FactormycobacteriaRNA Polymerasetranscription

Identifiers

PMID40552809
PMCPMC12288462

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.