Evidence map›Paper›PMID 40552733›Full record

ArticleParasite (Paris, France)2025

Genetic diversity and structure of Oncomelania hupensis snails in an area where Schistosoma japonicum transmission has been interrupted for nearly 30 years.

Ze-Ting Liu, Han-Qi Peng, Yu-Xin Qi, Xiao-Yan Wu, Qing Xu, Han-Xiang Zhang, Da-Bing Lu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Parasite (Paris, France), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ze-Ting Liu *Department of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China.
Han-Qi Peng *Department of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China - Community Health Service Center of Nicheng, Pudong New Area District, Shanghai 201306, P.R. China.
Yu-Xin QiDepartment of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China.
Xiao-Yan WuDepartment of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China.
Qing XuDepartment of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China.
Han-Xiang ZhangDepartment of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China.
Da-Bing LuDepartment of Epidemiology and Statistics, School of Public Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, MOE Key Laboratory of Geriatric Diseases and Immunology, Suzhou Medical College of Soochow University, Suzhou, Jiangsu 215123, P.R. China.ORCID 0000-0002-6396-9033

Funding

National Science Fundation of China 81971957
6 · The paper itself

Abstract

China was once a major endemic zone for Schistosoma japonicum, but decades of control efforts have dramatically reduced transmission. Suzhou City, in Jiangsu Province, a former hyperendemic area, achieved transmission interruption in 1995. However, the intermediate host Oncomelania hupensis persists and new habitats in non-endemic villages pose resurgence risks if parasites are reintroduced. To evaluate genetic resilience and dispersal potential, we analyzed six O. hupensis populations (214 snails) from ecologically distinct habitats in Wuzhong district, Suzhou (2018 to 2021): Guangfu (GF20 and GF21: wetlands), Jinting (JT18, JT19, and JT20: isolated island), and Dongshan (DS19: lakeside hills). Using nine microsatellite loci, we identified 91 alleles and assessed genetic diversity, structure, and demography. All populations exhibited low observed heterozygosity (Ho < 0.5), with bottlenecks detected in GF21, GF20, and JT20. Paradoxically, infinite effective population sizes (Ne) at 95% CI upper limits suggested retained adaptive potential. Significant genetic differentiation (F

Indexed as

Genetic VariationSchistosoma japonicumSchistosomiasis japonicaSnailsAllelesAnimalsChinaEcosystemHumansMicrosatellite RepeatsMicrosatellitesOncomelania hupensisPopulation genetic analysesSnail monitoring

Identifiers

PMID40552733
PMCPMC12187067

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.