Evidence map›Paper›PMID 40552649›Full record

ArticleBioconjugate chemistry2025

Chemo-Enzymatic Synthesis of Viscoelastic Pseudopeptidoglycan Networks.

Philipp Loibner, David Bučak-Gasser, Katharina Schober, Tobias Steindorfer, Monika Brandtner, Tobias Dorn, Tanja Wrodnigg, Dmytro Neshchadin, Georg Gescheidt-Demner, Matej Bračič and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioconjugate chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Philipp LoibnerInstitute of Chemistry and Technology of Biobased Systems, IBIOSYS, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.
David Bučak-GasserInstitute of Chemistry and Technology of Biobased Systems, IBIOSYS, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.
Katharina SchoberInstitute of Chemistry and Technology of Biobased Systems, IBIOSYS, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.
Tobias SteindorferInstitute of Chemistry and Technology of Biobased Systems, IBIOSYS, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.
Monika BrandtnerInstitute of Chemistry and Technology of Biobased Systems, IBIOSYS, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.
Tobias DornInstitute of Chemistry and Technology of Biobased Systems, IBIOSYS, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.ORCID 0009-0009-7513-9481
Tanja WrodniggInstitute of Chemistry and Technology of Biobased Systems, IBIOSYS, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.
Dmytro NeshchadinInstitute of Physical and Theoretical Chemistry, Graz University of Technology, 8010 Graz, Austria.ORCID 0000-0001-8918-1028
Georg Gescheidt-DemnerInstitute of Physical and Theoretical Chemistry, Graz University of Technology, 8010 Graz, Austria.
Matej BračičInstitute of Engineering Materials and Design, University of Maribor, Maribor 2000, Slovenia.
Florian LacknerInstitute of Chemistry and Technology of Biobased Systems, IBIOSYS, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.
Tamilselvan MohanInstitute of Chemistry and Technology of Biobased Systems, IBIOSYS, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.ORCID 0000-0002-8569-1642
Karin Stana KleinschekInstitute of Chemistry and Technology of Biobased Systems, IBIOSYS, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.ORCID 0000-0002-9189-0242
Rupert KarglInstitute of Chemistry and Technology of Biobased Systems, IBIOSYS, Graz University of Technology, Stremayrgasse 9, 8010 Graz, Austria.ORCID 0000-0003-4327-7053

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial peptidoglycans (PGs) are essential targets for antibiotics and immune cells. Chemical methods to reproduce PGs semisynthetically are tedious and wasteful. In this work, we describe a new approach to form pseudo-PGs (PPGs) using the protease papain and custom-made peptides conjugated to a glycan. The kinetics of formation is monitored by rheology and

Indexed as

PapainPeptidoglycanPolysaccharidesElasticityHumansRheologyViscosityPapainPeptidoglycanPolysaccharides

Identifiers

PMID40552649
PMCPMC12447390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.