Evidence map›Paper›PMID 40552420›Full record

ArticleHypertension (Dallas, Tex. : 1979)2025

Drinking Water NaCl Is Associated With Hypertension and Albuminuria: A Panel Study.

Asher Y Rosinger, Amanda McGrosky, Hannah Jacobson, Elena Hinz, Srishti Sadhir, Faith Wambua, Tom Otube, Lilian J Baker, Alison C Sherwood, Tiffany Chrissy-Mbeng and 18 more

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Article in Hypertension (Dallas, Tex. : 1979), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

28 authors.

Asher Y RosingerDepartment of Biobehavioral Health (A.Y.R., L.M.T.B., C.M., N.C.M., N.B., Z.F., M.T., Z.N., G.B., L.B.F.), Pennsylvania State University, University Park, PA.ORCID 0000-0001-9587-1447
Amanda McGroskyDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).ORCID 0000-0002-1110-4310
Hannah JacobsonDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).ORCID 0000-0002-9845-4515
Elena HinzDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).ORCID 0000-0002-7867-1336
Srishti SadhirDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).ORCID 0000-0002-3689-5892
Faith WambuaDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).
Tom OtubeKoobi Fora Field School, Kenya (T.O.).
Lilian J BakerDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).ORCID 0009-0000-0172-2003
Alison C SherwoodDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).
Tiffany Chrissy-MbengDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).
Lauren M T BroylesDepartment of Biobehavioral Health (A.Y.R., L.M.T.B., C.M., N.C.M., N.B., Z.F., M.T., Z.N., G.B., L.B.F.), Pennsylvania State University, University Park, PA.ORCID 0000-0003-2726-4930
Carey MusumeciDepartment of Biobehavioral Health (A.Y.R., L.M.T.B., C.M., N.C.M., N.B., Z.F., M.T., Z.N., G.B., L.B.F.), Pennsylvania State University, University Park, PA.
Natalie C MeriwetherDepartment of Biobehavioral Health (A.Y.R., L.M.T.B., C.M., N.C.M., N.B., Z.F., M.T., Z.N., G.B., L.B.F.), Pennsylvania State University, University Park, PA.
Nicole BobbieDepartment of Biobehavioral Health (A.Y.R., L.M.T.B., C.M., N.C.M., N.B., Z.F., M.T., Z.N., G.B., L.B.F.), Pennsylvania State University, University Park, PA.
Zoë FarrarDepartment of Biobehavioral Health (A.Y.R., L.M.T.B., C.M., N.C.M., N.B., Z.F., M.T., Z.N., G.B., L.B.F.), Pennsylvania State University, University Park, PA.ORCID 0009-0005-2465-0387
Madeleine ToddDepartment of Biobehavioral Health (A.Y.R., L.M.T.B., C.M., N.C.M., N.B., Z.F., M.T., Z.N., G.B., L.B.F.), Pennsylvania State University, University Park, PA.ORCID 0009-0000-7031-1777
Zee NguyenDepartment of Biobehavioral Health (A.Y.R., L.M.T.B., C.M., N.C.M., N.B., Z.F., M.T., Z.N., G.B., L.B.F.), Pennsylvania State University, University Park, PA.
Gabriella BergerDepartment of Biobehavioral Health (A.Y.R., L.M.T.B., C.M., N.C.M., N.B., Z.F., M.T., Z.N., G.B., L.B.F.), Pennsylvania State University, University Park, PA.
Leslie B FordDepartment of Biobehavioral Health (A.Y.R., L.M.T.B., C.M., N.C.M., N.B., Z.F., M.T., Z.N., G.B., L.B.F.), Pennsylvania State University, University Park, PA.ORCID 0000-0002-3904-5105
David R BraunDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).ORCID 0000-0002-7300-2635
Michael D HunterDepartment of Human Development and Family Studies (M.D.H.), Pennsylvania State University, University Park, PA.ORCID 0000-0002-3651-6709
Matthew J DouglassDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).ORCID 0000-0003-0559-2052
William B FarquharDepartment of Kinesiology and Applied Physiology, University of Delaware, Newark (W.B.F.).ORCID 0000-0003-0176-4486
W Larry KenneyDepartment of Kinesiology (W.L.K.), Pennsylvania State University, University Park, PA.ORCID 0000-0002-1326-8175
Jeff M SandsDepartment of Medicine, Renal Division, Emory University School of Medicine, Atlanta, GA (J.M.S.).ORCID 0000-0001-9822-0607
Rosemary NzunzaCenter for Virus Research, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya (R.N., H.P.). Global Health Institute, Duke University, Durham, NC.
Emmanuel K NdiemaDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).ORCID 0000-0002-1335-2924
Herman PontzerDepartment of Earth Sciences, National Museums of Kenya, Nairobi, Kenya (A.Y.R., A.M.G., H.J., E.H., S.S., F.W., L.J.B., A.C.S., T.C.-M., L.B.F., D.R.B., M.J.D., E.K.N., H.P.).ORCID 0000-0003-2397-6543

Funding

The Population Research Institute: Development CoreP2CHD041025 · NICHD · PENNSYLVANIA STATE UNIVERSITY, THE · PI Sarah Damaske · 2016 to 2026
$9.0M
Science CoreP2CHD065563 · NICHD · DUKE UNIVERSITY · PI James Moody · 2015 to 2026
$5.7M
Training Program in Social Environments and Population HealthT32HD007514 · NICHD · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI JOHN D. ICELAND · 1999 to 2026
$5.1M
Drinking water salinity in a hot-dry environment: Hydration, kidney function, and blood pressureR01ES035402 · NIEHS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Asher Y. Rosinger · 2024 to 2026
$2.1M
NICHD NIH HHS P2C HD041025NICHD NIH HHS P2C HD065563NICHD NIH HHS T32 HD007514NIEHS NIH HHS R01 ES035402
6 · The paper itself

Abstract

backgroundSalt leaching into freshwater is an emerging global environmental health concern. We tested the associations between drinking water salinity and blood pressure, hypertension, and albuminuria.

methodsWe conducted a 2-year panel study in 2022 and 2023 with 434 observations among 327 Daasanach adults aged >18 years in northern Kenya. Water sources were analyzed for overall salinity and ionic composition (sodium; chloride; calcium, potassium, magnesium). We measured resting blood pressure and classified hypertension stage 1 and stage 2. Urine samples were analyzed for albuminuria (≥30 mg/g albumin-to-creatinine ratio).

resultsDrinking water salinity was driven by sodium-chloride (mean=162.6 mg/L, SD=77.1), with low concentrations of calcium, potassium, and magnesium (mean=45 mg/L, SD=13.5). Across 2022 and 2023, 40.1% of adults had at least hypertension stage 1, 13.5% had hypertension stage 2, and 42.2% had albuminuria. Using random effects linear and logistic panel regressions fully adjusted for confounders, each 100 mg/L of drinking water sodium-chloride was associated with 4.5 mm Hg (95% CI, 2.4-6.6) and 3.3 mm Hg (95% CI, 2.2-4.5) increases in systolic and diastolic blood pressure, 3.0× the odds of at least hypertension stage 1 (95% CI, 1.49-5.83), 3.6× the odds of hypertension stage 2 (95% CI, 1.93-6.81), and 2.0× the odds of albuminuria (95% CI, 1.28-3.06). Calcium, potassium, and magnesium were unassociated with any outcomes. Hypertension stage 2 (but not hypertension stage 1) was associated with 2.6× (95% CI, 1.19-5.77) the odds of albuminuria.

conclusionsDrinking water sodium-chloride was associated with resting blood pressure, hypertension, and albuminuria in a population with few traditional lifestyle risk factors for chronic disease. Measuring specific salts in water helps untangle associations with hypertension.

Indexed as

AlbuminuriaDrinking WaterHypertensionSodium ChlorideAdultBlood PressureFemaleHumansKenyaMaleMiddle AgedDrinking WaterSodium Chloridealbuminuriablood pressuredrinking waterhypertensionsodium chloridewater salinity

Identifiers

PMID40552420
PMCPMC12270478

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