Evidence map›Paper›PMID 40552377›Full record

Trial reportAging & mental health2025

Brief mentalizing imagery therapy reduces stress and enhances positive psychological traits in family dementia caregivers: mediation by mindfulness.

Paulina Gutierrez-Ramirez, Liliana A Ramirez Gomez, Miranda Zea, Maren Nyer, Kimberly Dueck, Finale Doshi-Velez, Felipe A Jain

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Aging & mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paulina Gutierrez-RamirezDepression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Liliana A Ramirez GomezMemory Disorders Division, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA.
Miranda ZeaDepression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Maren NyerDepression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Kimberly DueckDepression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Finale Doshi-VelezDepartment of Computer Science, Harvard University, Cambridge, MA, USA.
Felipe A JainDepression Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.

Funding

Mobile app delivered Mentalizing Imagery Therapy to augment remote family dementia caregiver skills training: a pilot randomized, controlled trial with outcomes assessment using digital phenotypingK76AG064390 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI JAIN, FELIPE A. · 2020 to 2024
$1.5M
NIA NIH HHS K76 AG064390
6 · The paper itself

Abstract

objectivesFamily dementia caregivers exhibit high rates of chronic psychological stress. We aimed to determine the impact of mentalizing imagery therapy (MIT), a mindfulness and guided imagery approach, on perceived stress and positive psychological traits. We further investigated the role of dispositional mindfulness on these effects.

methodThis analysis of secondary outcomes drew from a pilot randomized controlled trial (

resultsMIT demonstrated statistically significant benefits relative to the support group for perceived stress, resilience, spiritual well-being, and other positive traits. Changes from baseline to post-group in mindfulness significantly mediated the relationships between group and most outcomes.

conclusionIn this pilot trial, MIT reduced perceived stress and improved positive psychological traits. Mediation by dispositional mindfulness was demonstrated. Future research in larger samples should be aimed at confirming the benefits of short-term MIT on reducing stress and improving positive psychological traits, and studying the time course of mediation effects by mindfulness.

Indexed as

CaregiversDementiaImagery, PsychotherapyMentalizationMindfulnessStress, PsychologicalAgedFemaleHumansMaleMiddle AgedPilot ProjectsResilience, PsychologicalcaregivingeudaimoniaFamily caregiversmindfulnessperceived stresspsychological and social aspectsquality of life/well-beingresilienceStress/burden

Identifiers

PMID40552377
PMCPMC12229082

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.