Evidence map›Paper›PMID 40552341›Full record

ReviewClinical, cosmetic and investigational dermatology2025

A Bibliometric Analysis and Visualization of Research Trends and Hotspots in Actinic Keratosis Based on Web of Science.

Zilin Cheng, Zeyun Qiao, Shaojie An, Jinghua Liu, Wenyi Ma, Pingsheng Hao

Abstract readReview
In one paragraph

Review in Clinical, cosmetic and investigational dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zilin Cheng *Clinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, People's Republic of China.
Zeyun Qiao *Clinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, People's Republic of China.
Shaojie AnClinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, People's Republic of China.
Jinghua LiuClinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, People's Republic of China.
Wenyi MaClinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, People's Republic of China.ORCID 0009-0005-6614-5450
Pingsheng HaoClinical Medical College, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, People's Republic of China.ORCID 0000-0002-0376-6269

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Actinic keratosis (AK) is a precancerous intraepidermal lesion characterized by atypical keratinocyte proliferation. In recent years, research on AK has made continuous progress, but there has been no bibliometric study on it. This study aims to use bibliometric methods to analyze the research and treatment hotspots of AK in recent years, in order to further understand the development direction and frontiers of this field. Methods: Core literature related to AK was retrieved from the Web of Science Core Collection (WoSCC) database. CiteSpace and VOSviewer software were employed to conduct a detailed analysis based on publication output, countries/regions, research institutions, journals, authors, and keywords. Results: A total of 2,796 documents were included in this study. The United States, Germany, and Italy emerged as the leading contributors to AK research, with the University of Copenhagen identified as the most prolific research institution. Among authors, Pellacani G has published the highest number of articles, while the Journal of the European Academy of Dermatology and Venereology ranks as the most influential journal in this field. The main research hotspots and frontiers in the field of AK are as follows: (1) Molecular mechanisms of malignant transformation to cutaneous squamous cell carcinoma (cSCC), particularly involving genomic instability (eg, TP53 mutations); (2) Personalized therapies optimized through immune profiling, genetic biomarkers, and lesion morphology; (3) Emerging frontiers include non-invasive diagnostic technologies and treatment monitoring, which are receiving significant attention. Conclusion: This study summarizes the current research status and key areas of focus in AK, providing a foundation for clinical decision-making and guiding future research directions.

Indexed as

actinic keratosisbibliometricscutaneous squamous cell carcinomavisualization

Identifiers

PMID40552341
PMCPMC12184693

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.