ArticleFrontiers in oncology2025
A multivariate model of IVIM-DWI in the preoperative diagnosis of tumor budding grade in rectal cancer.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: The aim of this study was to explore the application value of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) in the preoperative evaluation of the tumor budding (TB) grade in patients with rectal cancer (RC). Methods: Patients with RC who underwent rectum resection from January 2018 to October 2023 were collected retrospectively. All patients underwent magnetic resonance (MR) examination, including collection of IVIM sequences, within 1 week before surgery. Among them, 17 low-grade and 13 intermediate-grade budding cases were classified into the low-intermediate-grade group, while 30 high-grade budding cases were classified as high grade. After processing the IVIM sequences, the apparent diffusion coefficient (ADC) from the mono-exponential (ME) model; Results: A total of 60 patients with RC were enrolled. Significant differences between low-intermediate and high grade were found in Conclusion: The combined model constructed using multiple IVIM mathematical model parameters and clinical and imaging factors could be used as a noninvasive tool to facilitate the preoperative auxiliary diagnosis of TB in RC.
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