ArticleOncology letters2025
Dosimetric comparison and prognostic analysis of helical tomotherapy vs. intensity-modulated radiation therapy in locally advanced cervical cancer.
Article in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Spatially fractionated radiation therapy for bulky tumors: a systematic review of clinical outcomes and dosimetric challenges.Radiation oncology (London, England) · 2026Pooled it
- Induction toripalimab plus chemotherapy sequential concurrent chemoradiotherapy with nimotuzumab followed by toripalimab maintenance in stage IVB hypopharyngeal squamous cell carcinoma: a single-arm phase 2 study.Journal for immunotherapy of cancer · 2026Trial
- Optimizing safety and efficacy in radiotherapy for external auditory canal cancer.Oncology letters · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cervical cancer is a major oncological challenge worldwide, particularly in its locally advanced stages where optimal radiotherapy strategies are essential. The present study aimed to compare the dosimetric characteristics, clinical efficacy and radiation-related toxicity of helical tomotherapy (HT) and intensity-modulated radiation therapy (IMRT) in the treatment of locally advanced cervical cancer, providing scientific evidence to optimize radiotherapy strategies. A retrospective analysis was performed using data from 100 patients with locally advanced cervical cancer treated at the Cangzhou Integrated Traditional Chinese and Western Medicine Hospital between January 2015 and December 2023. Among them, 50 patients received HT and 50 received IMRT for whole pelvic radiotherapy. Comparisons included dosimetric parameters of target areas and organs-at-risk (OARs), short-term efficacy (based on Response Evaluation Criteria in Solid Tumors 1.1), long-term outcomes [5-year overall survival (OS) and progression-free survival (PFS)] and radiation-related toxicity (graded using the Radiation Therapy Oncology Group criteria). The results revealed that HT demonstrated significantly greater conformity index and homogeneity index values compared with that of IMRT (P<0.05), with significantly reduced high-dose exposure (V
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