Evidence map›Paper›PMID 40552236›Full record

SynthesisFrontiers in public health2025

Understanding out-of-pocket expenditure in India: a systematic review.

Sagarika Kamath, Jeffin Maliyekkal, S Elstin Anbu Raj, R J Varshini, Helmut Brand, Andria Sirur, Vishwajeet Singh, Vidya Prabhu, Kumar Sumit, Rajesh Kamath

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  9. Bridging the Gap: Addressing Geographic and Socioeconomic Inequities in Access to Cardiac Catheterization in India.Journal of the Society for Cardiovascular Angiography & Interventions · 2026
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  13. Patient Engagement in Treatment and its Determinants among Rural Indian Adults with Hypertension and Diabetes.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sagarika KamathDepartment of International Health, Care and Public Health Research Institute-CAPHRI, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.
Jeffin MaliyekkalDepartment of Social and Health Innovation, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, India.
S Elstin Anbu RajCentre for Evidence-Informed Decision Making, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, India.
R J VarshiniDepartment of Healthcare and Hospital Management, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, India.
Helmut BrandDepartment of International Health, Care and Public Health Research Institute-CAPHRI, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.
Andria SirurManipal School of Commerce and Economics, Manipal Academy of Higher Education, Manipal, India.
Vishwajeet SinghDirectorate of Online Education, Manipal Academy of Higher Education, Manipal, India.
Vidya PrabhuDepartment of Global Public Health Policy and Governance, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, India.
Kumar SumitDepartment of Global Public Health Policy and Governance, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, India.
Rajesh KamathDepartment of Healthcare and Hospital Management, Prasanna School of Public Health, Manipal Academy of Higher Education, Manipal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Out-of-pocket expenditure (OOPE) constitutes a substantial portion of healthcare costs in India, accounting for 47.1% of the Total Health Expenditure in 2019-20. Despite a decline from previous years, OOPE remains a significant financial burden, contributing to catastrophic health expenditures and impoverishment for households. Methods: A systematic review was conducted to analyze factors influencing out-of-pocket expenditures (OOPE) in India. The review adhered to predefined inclusion and exclusion criteria. Search terms were tailored to the syntax of each database to maximize retrieval, using combinations of keywords such as "out of pocket," "India," and "national survey." A total of 702 citations were retrieved (PubMed: 185, Web of Science: 183, Scopus: 334), with 316 identified as duplicates. After title and abstract screening of 386 citations, 128 articles were subjected to full-text review, leading to the inclusion of 36 studies. A narrative synthesis and thematic analysis identified determinants of OOPE in the Indian healthcare context, with findings organized in tables and descriptive formats to address study heterogeneity and enhance interpretation. Results: This systematic and rigorous methodology ensures a comprehensive and reliable understanding of the determinants of OOPE in the Indian healthcare context. Eleven themes emerged from the review: (1) source of care and disease/ condition, (2) place of residence, (3) economic status, (4) components of OOPE, (5) age, (6) gender, (7) strategies for coping with OOPE, (8) educational attainment, (9) OOPE and institutional deliveries, (11) health insurance. Discussion: India's heavy reliance on OOPE emphasizes healthcare gaps, necessitating reforms in public investment, insurance, primary care, and affordable access to ensure equity and financial protection. The lack of equitable healthcare financing instigates the challenges, leading to widespread reliance on distress financing methods.

Indexed as

Financing, PersonalHealth ExpendituresHumansIndiaAyushman BharatNational Family Health Survey (NFHS)National Sample Survey Office (NSSO)out of pocket expenditurepublicly funded health insurance

Identifiers

PMID40552236
PMCPMC12183295

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.