Evidence map›Paper›PMID 40552044›Full record

ArticlePeerJ2025

Psychological distress and pregnancy outcomes in early-stage gestational hypertension: a case-control study from China.

Xilian Li, Rongmin Wang, Xian Xia, Dongdong Shi, Lili Gong, Biao Gao

Abstract read
In one paragraph

Article in PeerJ, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xilian Li *Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.
Rongmin Wang *Obstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.ORCID 0000-0002-0643-7698
Xian XiaObstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.
Dongdong ShiObstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.
Lili GongObstetrics & Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.
Biao GaoTeaching and Research Support Center, Naval Medical University, Shanghai, China.ORCID 0000-0002-8871-1733

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to elucidate the pathophysiological role of psychological distress in early-stage gestational hypertension (GH) through comprehensive assessment of its regulatory effects on disease progression and association with adverse pregnancy outcomes, thereby providing evidence-based support for early screening and intervention strategies. Methods: We conducted a prospective case-control study involving 446 patients with early-stage GH (diagnostic criteria: new-onset hypertension after 20 weeks of gestation, blood pressure ≥140/90 mmHg without proteinuria) and 200 normotensive pregnant women as controls. Psychological distress was assessed using the Self-Rated Anxiety Scale (SAS). A multidimensional statistical approach, including univariate analysis and multivariate logistic regression, was employed to systematically explore the risk factors that influence psychological distress. Pregnancy and perinatal outcomes were compared using Chi-square tests and t-tests. Results: The study revealed a markedly elevated prevalence of psychological distress in the early-stage GH group (20.9%) compared to controls (7.0%, Conclusions: This study provides a systematic characterization of psychological distress patterns in early stage GH patients and their potential impact on disease progression. Findings highlight the critical importance of integrating routine psychological screening and early intervention strategies into prenatal care for patients with GH to optimize maternal and neonatal outcomes.

Indexed as

Hypertension, Pregnancy-InducedPregnancy OutcomePsychological DistressAdultCase-Control StudiesChinaFemaleHumansPregnancyProspective StudiesRisk FactorsAnxietyDepressionEarly-stage gestational hypertensionPregnancy outcomesPsychological status

Identifiers

PMID40552044
PMCPMC12184673

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.